ENSG00000132436


Homo sapiens

Features
Gene ID: ENSG00000132436
  
Biological name :FIGNL1
  
Synonyms : fidgetin like 1 / FIGNL1 / Q6PIW4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p12.1
Gene start: 50444128
Gene end: 50542535
  
Corresponding Affymetrix probe sets: 1552921_a_at (Human Genome U133 Plus 2.0 Array)   222843_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000409281
Ensembl peptide - ENSP00000403012
Ensembl peptide - ENSP00000409674
Ensembl peptide - ENSP00000484551
Ensembl peptide - ENSP00000483543
Ensembl peptide - ENSP00000483126
Ensembl peptide - ENSP00000481751
Ensembl peptide - ENSP00000410811
Ensembl peptide - ENSP00000349356
Ensembl peptide - ENSP00000378924
Ensembl peptide - ENSP00000388471
Ensembl peptide - ENSP00000394070
Ensembl peptide - ENSP00000399997
Ensembl peptide - ENSP00000402957
NCBI entrez gene - 63979     See in Manteia.
OMIM - 615383
RefSeq - NM_022116
RefSeq - NM_001042762
RefSeq - NM_001287492
RefSeq - NM_001287493
RefSeq - NM_001287494
RefSeq - NM_001287495
RefSeq - NM_001287496
RefSeq - XM_011515470
RefSeq - XM_017012501
RefSeq - XM_017012502
RefSeq Peptide - NP_001333494
RefSeq Peptide - NP_001274425
RefSeq Peptide - NP_001333489
RefSeq Peptide - NP_001333490
RefSeq Peptide - NP_001333491
RefSeq Peptide - NP_001333492
RefSeq Peptide - NP_001333493
RefSeq Peptide - NP_071399
RefSeq Peptide - NP_001036227
RefSeq Peptide - NP_001274421
RefSeq Peptide - NP_001274422
RefSeq Peptide - NP_001274423
RefSeq Peptide - NP_001274424
swissprot - Q6PIW4
swissprot - C9JHJ4
swissprot - C9JSC4
swissprot - C9JP37
swissprot - C9JKI6
swissprot - C9JTG6
swissprot - C9JTB2
Ensembl - ENSG00000132436
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fignl1ENSDARG00000016427Danio rerio
 ENSGALG00000026363Gallus gallus
 Fignl1ENSMUSG00000035455Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FIGN / Q5HY92 / fidgetin, microtubule severing factorENSG0000018226339
SPAST / Q9UBP0 / spastinENSG0000002157430
A6NMB9 / FIGNL2 / fidgetin like 2ENSG0000026130827
IQCA1 / Q86XH1 / IQ motif containing with AAA domain 1ENSG0000013232117
IQCA1L / IQ motif containing with AAA domain 1 likeENSG0000027868516


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR015415  Vps4 oligomerisation, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation ISS
 biological_processGO:0007140 male meiotic nuclear division ISS
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IDA
 biological_processGO:0033687 osteoblast proliferation ISS
 biological_processGO:0043066 negative regulation of apoptotic process ISS
 biological_processGO:0046034 ATP metabolic process ISS
 biological_processGO:0051726 regulation of cell cycle ISS
 biological_processGO:0071479 cellular response to ionizing radiation IDA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0000228 nuclear chromosome IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity ISS
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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