ENSMUSG00000035455


Mus musculus

Features
Gene ID: ENSMUSG00000035455
  
Biological name :Fignl1
  
Synonyms : Fidgetin-like protein 1 / Fignl1 / Q8BPY9
  
Possible biological names infered from orthology : fidgetin like 1 / Q6PIW4
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A1
Gene start: 11787431
Gene end: 11808962
  
Corresponding Affymetrix probe sets: 10384373 (MoGene1.0st)   1422430_at (Mouse Genome 430 2.0 Array)   1460746_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127489
Ensembl peptide - ENSMUSP00000105290
Ensembl peptide - ENSMUSP00000119528
Ensembl peptide - ENSMUSP00000036932
Ensembl peptide - ENSMUSP00000126340
NCBI entrez gene - 60530     See in Manteia.
MGI - MGI:1890648
RefSeq - XM_011243738
RefSeq - NM_001163359
RefSeq - NM_001163360
RefSeq - NM_021891
RefSeq - XM_006514767
RefSeq - XM_011243737
RefSeq Peptide - NP_001156831
RefSeq Peptide - NP_001156832
RefSeq Peptide - NP_068691
swissprot - Q5SWU3
swissprot - Q8BPY9
Ensembl - ENSMUSG00000035455
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fignl1ENSDARG00000016427Danio rerio
 ENSGALG00000026363Gallus gallus
 FIGNL1ENSG00000132436Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fign / Q9ERZ6 / Fidgetin / Q5HY92* / fidgetin, microtubule severing factor*ENSMUSG0000007532436
Spast / Q9QYY8 / Spastin / Q9UBP0*ENSMUSG0000002406829
Fignl2 / fidgetin like 2 / A6NMB9*ENSMUSG0000009544024
Iqca / Q9CUL5 / IQ and AAA domain-containing protein 1 / IQCA1* / Q86XH1* / IQ motif containing with AAA domain 1*ENSMUSG0000002630117
A6H690 / 4931409K22Rik / IQ and AAA domain-containing protein 1-like / IQCA1L* / IQ motif containing with AAA domain 1 like*ENSMUSG0000003819916


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR015415  Vps4 oligomerisation, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IMP
 biological_processGO:0007140 male meiotic nuclear division IMP
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IEA
 biological_processGO:0033687 osteoblast proliferation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0046034 ATP metabolic process ISS
 biological_processGO:0051726 regulation of cell cycle IMP
 biological_processGO:0071479 cellular response to ionizing radiation IEA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0000228 nuclear chromosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity ISS
 molecular_functionGO:0016887 ATPase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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