ENSG00000182400


Homo sapiens

Features
Gene ID: ENSG00000182400
  
Biological name :TRAPPC6B
  
Synonyms : Q86SZ2 / trafficking protein particle complex 6B / TRAPPC6B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q21.1
Gene start: 39147811
Gene end: 39170532
  
Corresponding Affymetrix probe sets: 225537_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000335171
Ensembl peptide - ENSP00000451711
Ensembl peptide - ENSP00000452236
Ensembl peptide - ENSP00000330289
Ensembl peptide - ENSP00000450670
NCBI entrez gene - 122553     See in Manteia.
OMIM - 610397
RefSeq - XM_017020964
RefSeq - NM_001079537
RefSeq - NM_177452
RefSeq - XM_011536409
RefSeq Peptide - NP_001073005
RefSeq Peptide - NP_803235
swissprot - G3V4C3
swissprot - Q86SZ2
swissprot - G3V2H7
Ensembl - ENSG00000182400
  
Related genetic diseases (OMIM): 617862 - Neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy, 617862
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trappc6bENSDARG00000016463Danio rerio
 TRAPPC6BENSGALG00000010157Gallus gallus
 Q9D289ENSMUSG00000020993Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O75865 / TRAPPC6A / trafficking protein particle complex 6AENSG0000000725556


Protein motifs (from Interpro)
Interpro ID Name
 IPR007194  Transport protein particle (TRAPP) component
 IPR024096  NO signalling/Golgi transport ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0048193 Golgi vesicle transport IEA
 biological_processGO:0048208 COPII vesicle coating TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005801 cis-Golgi network IBA
 cellular_componentGO:0005802 trans-Golgi network IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0030008 TRAPP complex IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity TAS


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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