ENSG00000182463


Homo sapiens

Features
Gene ID: ENSG00000182463
  
Biological name :TSHZ2
  
Synonyms : Q9NRE2 / teashirt zinc finger homeobox 2 / TSHZ2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.2
Gene start: 52972407
Gene end: 53495330
  
Corresponding Affymetrix probe sets: 220213_at (Human Genome U133 Plus 2.0 Array)   235616_at (Human Genome U133 Plus 2.0 Array)   235815_at (Human Genome U133 Plus 2.0 Array)   238577_s_at (Human Genome U133 Plus 2.0 Array)   243940_at (Human Genome U133 Plus 2.0 Array)   244521_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333114
Ensembl peptide - ENSP00000474159
Ensembl peptide - ENSP00000475114
Ensembl peptide - ENSP00000487408
Ensembl peptide - ENSP00000360552
NCBI entrez gene - 128553     See in Manteia.
OMIM - 614118
RefSeq - XM_017027641
RefSeq - NM_001193421
RefSeq - NM_173485
RefSeq - XM_017027640
RefSeq Peptide - NP_775756
RefSeq Peptide - NP_001180350
swissprot - Q9NRE2
swissprot - S4R3C8
swissprot - B1H0U8
Ensembl - ENSG00000182463
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tshz2ENSDARG00000079201Danio rerio
 TSHZ2ENSGALG00000007809Gallus gallus
 Tshz2ENSMUSG00000047907Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TSHZ1 / Q6ZSZ6 / teashirt zinc finger homeobox 1ENSG0000017998151
TSHZ3 / Q63HK5 / teashirt zinc finger homeobox 3ENSG0000012129748


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR027008  Teashirt family
 IPR027010  Teashirt homologue 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0010468 regulation of gene expression IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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