ENSG00000121297


Homo sapiens

Features
Gene ID: ENSG00000121297
  
Biological name :TSHZ3
  
Synonyms : Q63HK5 / teashirt zinc finger homeobox 3 / TSHZ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q12
Gene start: 31274945
Gene end: 31349547
  
Corresponding Affymetrix probe sets: 223392_s_at (Human Genome U133 Plus 2.0 Array)   223393_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000240587
Ensembl peptide - ENSP00000475613
NCBI entrez gene - 57616     See in Manteia.
OMIM - 614119
RefSeq - NM_020856
RefSeq Peptide - NP_065907
swissprot - Q63HK5
swissprot - U3KQ78
Ensembl - ENSG00000121297
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tshz3aENSDARG00000087394Danio rerio
 tshz3bENSDARG00000103361Danio rerio
 TSHZ3ENSGALG00000004528Gallus gallus
 Tshz3ENSMUSG00000021217Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TSHZ1 / Q6ZSZ6 / teashirt zinc finger homeobox 1ENSG0000017998156
TSHZ2 / Q9NRE2 / teashirt zinc finger homeobox 2ENSG0000018246346


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR026810  Teashirt homologue 3
 IPR027008  Teashirt family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0002087 regulation of respiratory gaseous exchange by neurological system process ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0051968 positive regulation of synaptic transmission, glutamatergic ISS
 biological_processGO:0060291 long-term synaptic potentiation ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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