ENSMUSG00000021217


Mus musculus

Features
Gene ID: ENSMUSG00000021217
  
Biological name :Tshz3
  
Synonyms : teashirt zinc finger homeobox 3 / Tshz3
  
Possible biological names infered from orthology : Q63HK5
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B2
Gene start: 36698118
Gene end: 36773553
  
Corresponding Affymetrix probe sets: 10552245 (MoGene1.0st)   1435337_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021641
NCBI entrez gene - 243931     See in Manteia.
MGI - MGI:2442819
RefSeq - XM_017322238
RefSeq - NM_172298
RefSeq - XM_006539965
RefSeq - XM_006539966
RefSeq - XM_006539961
RefSeq - XM_006539963
RefSeq Peptide - NP_758502
swissprot - A0A0R4J017
Ensembl - ENSMUSG00000021217
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tshz3aENSDARG00000087394Danio rerio
 tshz3bENSDARG00000103361Danio rerio
 TSHZ3ENSGALG00000004528Gallus gallus
 TSHZ3ENSG00000121297Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tshz1 / Q5DTH5 / Teashirt homolog 1 / Q6ZSZ6* / teashirt zinc finger homeobox 1*ENSMUSG0000004698257
Tshz2 / Q68FE9 / teashirt zinc finger family member 2 / Q9NRE2* / teashirt zinc finger homeobox 2*ENSMUSG0000004790745


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR013087  Zinc finger C2H2-type
 IPR026810  Teashirt homologue 3
 IPR027008  Teashirt family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0000534 abnormal ureter morphology "anomalous structure of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0000536 hydroureter "distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

Allelic Composition: Tshz3tm1Lafa/Tshz3+
Genetic Background: involves: 129P2/OlaHsd * CD-1

 MP:0001177 atelectasis "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0001404 no spontaneous movement "failure to make any change in position or posture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0003586 ureter dilation "abnormal distention of the ureter due to accumulation of fluid" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0003672 abnormal ureter development "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0004194 abnormal kidney pelvis morphology "any structural anomaly of the funnel shaped proximal portion of the ureter that is formed by convergence of the major calices" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0005498 hyporesponsive to tactile stimuli "reduced reflex action normally induced by touch or pain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0011426 abnormal ureter smooth muscle morphology "any structural anomaly of the smooth muscle tissue surrounding the epithelium of the ureter" [MGI:anna]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

 MP:0011480 impaired ureteric peristalsis "any anomaly in the wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, thus propelling urine from the kidney pelvis to the urinary bladder" [MGI:anna]
Show

Allelic Composition: Ncoa6tm1.1Jkr/Ncoa6tm1.1Jkr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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