ENSMUSG00000047907


Mus musculus

Features
Gene ID: ENSMUSG00000047907
  
Biological name :Tshz2
  
Synonyms : Q68FE9 / teashirt zinc finger family member 2 / Tshz2
  
Possible biological names infered from orthology : Q9NRE2 / teashirt zinc finger homeobox 2
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H3
Gene start: 169633013
Gene end: 170071816
  
Corresponding Affymetrix probe sets: 10478928 (MoGene1.0st)   1428026_at (Mouse Genome 430 2.0 Array)   1435385_at (Mouse Genome 430 2.0 Array)   1459250_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120013
Ensembl peptide - ENSMUSP00000140884
Ensembl peptide - ENSMUSP00000104785
Ensembl peptide - ENSMUSP00000104787
Ensembl peptide - ENSMUSP00000118550
NCBI entrez gene - 228911     See in Manteia.
MGI - MGI:2153084
RefSeq - XM_011239515
RefSeq - XM_017317966
RefSeq - XM_017317967
RefSeq - XM_017317968
RefSeq - NM_080455
RefSeq Peptide - NP_536703
swissprot - Q8K350
swissprot - A0A087WS38
swissprot - Q68FE9
swissprot - A0A0A0MQI3
Ensembl - ENSMUSG00000047907
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tshz2ENSDARG00000079201Danio rerio
 TSHZ2ENSGALG00000007809Gallus gallus
 TSHZ2ENSG00000182463Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tshz1 / Q5DTH5 / Teashirt homolog 1 / Q6ZSZ6* / teashirt zinc finger homeobox 1*ENSMUSG0000004698251
Tshz3 / teashirt zinc finger homeobox 3 / Q63HK5*ENSMUSG0000002121747


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR026939  At2g23090-like
 IPR027008  Teashirt family
 IPR027010  Teashirt homologue 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0010468 regulation of gene expression IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003694 failure to hatch from the zona pellucida "the embryo fails to break out of the thick solid transparent outer membrane that surrounds the developing ovum and embryo prior to implantation, may be seen in vivo or in cultured embryos" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Faslpr/Faslpr
Genetic Background: MRL/Mp-Faslpr atms

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Faslpr/Faslpr
Genetic Background: MRL/Mp-Faslpr atms

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr