ENSG00000183576


Homo sapiens

Features
Gene ID: ENSG00000183576
  
Biological name :SETD3
  
Synonyms : Q86TU7 / SETD3 / SET domain containing 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.2
Gene start: 99397746
Gene end: 99480889
  
Corresponding Affymetrix probe sets: 212465_at (Human Genome U133 Plus 2.0 Array)   229940_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398966
Ensembl peptide - ENSP00000396870
Ensembl peptide - ENSP00000408602
Ensembl peptide - ENSP00000486445
Ensembl peptide - ENSP00000327436
Ensembl peptide - ENSP00000327910
Ensembl peptide - ENSP00000350174
NCBI entrez gene - 84193     See in Manteia.
OMIM - 615671
RefSeq - XM_017021702
RefSeq - XM_011537233
RefSeq - XM_011537234
RefSeq - XM_011537235
RefSeq - XM_017021699
RefSeq - XM_017021700
RefSeq - XM_017021701
RefSeq - NM_032233
RefSeq - NM_199123
RefSeq - XM_005268127
RefSeq - XM_011537231
RefSeq - XM_011537232
RefSeq Peptide - NP_115609
RefSeq Peptide - NP_954574
swissprot - C9K0W5
swissprot - Q86TU7
swissprot - A0A024R6K3
swissprot - Q6NXR6
Ensembl - ENSG00000183576
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 setd3ENSDARG00000016513Danio rerio
 SETD3ENSGALG00000034802Gallus gallus
 Setd3ENSMUSG00000056770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SETD4 / Q9NVD3 / SET domain containing 4ENSG0000018591715


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR015353  Rubisco LSMT, substrate-binding domain
 IPR025785  Histone-lysine N-methyltransferase, SETD3
 IPR036464  Rubisco LSMT, substrate-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010452 histone H3-K36 methylation IEA
 biological_processGO:0018022 peptidyl-lysine methylation IEA
 biological_processGO:0018023 peptidyl-lysine trimethylation IEA
 biological_processGO:0018026 peptidyl-lysine monomethylation IEA
 biological_processGO:0018027 peptidyl-lysine dimethylation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0051149 positive regulation of muscle cell differentiation IEA
 biological_processGO:0051568 histone H3-K4 methylation IBA
 biological_processGO:1903506 regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) IBA
 molecular_functionGO:0046975 histone methyltransferase activity (H3-K36 specific) IEA


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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