ENSG00000184357


Homo sapiens

Features
Gene ID: ENSG00000184357
  
Biological name :HIST1H1B
  
Synonyms : HIST1H1B / histone cluster 1 H1 family member b / P16401
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p22.1
Gene start: 27866849
Gene end: 27867529
  
Corresponding Affymetrix probe sets: 214534_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000330074
NCBI entrez gene - 3009     See in Manteia.
OMIM - 142711
RefSeq - NM_005322
RefSeq Peptide - NP_005313
swissprot - P16401
Ensembl - ENSG00000184357
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 histh1lENSDARG00000035519Danio rerio
 si:ch1073-153i20.4ENSDARG00000105350Danio rerio
 si:ch1073-159d7.7ENSDARG00000074012Danio rerio
 si:ch211-103n10.5ENSDARG00000077504Danio rerio
 si:ch211-113a14.18ENSDARG00000051735Danio rerio
 si:ch211-113a14.24ENSDARG00000051718Danio rerio
 si:ch73-368j24.11ENSDARG00000105430Danio rerio
 si:ch73-368j24.12ENSDARG00000105502Danio rerio
 si:ch73-36p18.1ENSDARG00000115766Danio rerio
 si:dkey-108k21.10ENSDARG00000075508Danio rerio
 si:dkey-108k21.14ENSDARG00000110841Danio rerio
 si:dkey-108k21.21ENSDARG00000091905Danio rerio
 si:dkey-23a13.17ENSDARG00000105328Danio rerio
 si:dkey-23a13.9ENSDARG00000105431Danio rerio
 si:dkey-261m9.12ENSDARG00000032637Danio rerio
 zgc:110216ENSDARG00000077456Danio rerio
 zgc:110425ENSDARG00000058479Danio rerio
 zgc:153405ENSDARG00000096992Danio rerio
 zgc:163061ENSDARG00000076766Danio rerio
 zgc:163061ENSDARG00000075538Danio rerio
 ENSGALG00000011747Gallus gallus
 HIST1H111RENSGALG00000011783Gallus gallus
 P08284ENSGALG00000031874Gallus gallus
 P08285ENSGALG00000037167Gallus gallus
 P08286ENSGALG00000031159Gallus gallus
 Gm6970ENSMUSG00000091230Mus musculus
 P43276ENSMUSG00000058773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P10412 / HIST1H1E / histone cluster 1 H1 family member eENSG0000016829885
P16403 / HIST1H1C / histone cluster 1 H1 family member cENSG0000018783777
P16402 / HIST1H1D / histone cluster 1 H1 family member dENSG0000012457577
Q02539 / HIST1H1A / histone cluster 1 H1 family member aENSG0000012461067
P22492 / HIST1H1T / histone cluster 1 H1 family member tENSG0000018747549


Protein motifs (from Interpro)
Interpro ID Name
 IPR005818  Linker histone H1/H5, domain H15
 IPR005819  Histone H5
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006325 chromatin organization IMP
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0030307 positive regulation of cell growth IMP
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0051574 positive regulation of histone H3-K9 methylation IMP
 biological_processGO:0071169 establishment of protein localization to chromatin IMP
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005720 nuclear heterochromatin IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0031490 chromatin DNA binding IMP
 molecular_functionGO:0042826 histone deacetylase binding IPI


Pathways (from Reactome)
Pathway description
Activation of DNA fragmentation factor
Formation of Senescence-Associated Heterochromatin Foci (SAHF)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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