ENSG00000185189


Homo sapiens

Features
Gene ID: ENSG00000185189
  
Biological name :NRBP2
  
Synonyms : NRBP2 / nuclear receptor binding protein 2 / Q9NSY0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.3
Gene start: 143833594
Gene end: 143840974
  
Corresponding Affymetrix probe sets: 225949_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432374
Ensembl peptide - ENSP00000414055
Ensembl peptide - ENSP00000431280
NCBI entrez gene - 340371     See in Manteia.
OMIM - 615563
RefSeq - XM_017013383
RefSeq - XM_017013379
RefSeq - XM_017013380
RefSeq - XM_017013381
RefSeq - XM_017013382
RefSeq - NM_178564
RefSeq - XM_017013378
RefSeq Peptide - NP_848659
swissprot - H0YCB1
swissprot - E9PR11
swissprot - Q9NSY0
Ensembl - ENSG00000185189
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nrbp2aENSDARG00000032951Danio rerio
 nrbp2bENSDARG00000009626Danio rerio
 NRBP2ENSGALG00000029760Gallus gallus
 Nrbp2ENSMUSG00000075590Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRBP1 / Q9UHY1 / nuclear receptor binding protein 1ENSG0000011521661
WNK3 / Q9BYP7 / WNK lysine deficient protein kinase 3ENSG0000019663229
WNK2 / Q9Y3S1 / WNK lysine deficient protein kinase 2ENSG0000016523829
WNK1 / Q9H4A3 / WNK lysine deficient protein kinase 1ENSG0000006023728
WNK4 / Q96J92 / WNK lysine deficient protein kinase 4ENSG0000012656225


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0016242 negative regulation of macroautophagy IMP
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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