ENSG00000115216


Homo sapiens

Features
Gene ID: ENSG00000115216
  
Biological name :NRBP1
  
Synonyms : NRBP1 / nuclear receptor binding protein 1 / Q9UHY1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p23.3
Gene start: 27427790
Gene end: 27442259
  
Corresponding Affymetrix probe sets: 217765_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415406
Ensembl peptide - ENSP00000369181
Ensembl peptide - ENSP00000369192
Ensembl peptide - ENSP00000403916
Ensembl peptide - ENSP00000233557
NCBI entrez gene - 29959     See in Manteia.
OMIM - 606010
RefSeq - NM_001321359
RefSeq - NM_001321357
RefSeq - NM_001321358
RefSeq - NM_001321361
RefSeq - NM_001321362
RefSeq - NM_001321363
RefSeq - NM_013392
RefSeq Peptide - NP_001308292
RefSeq Peptide - NP_037524
RefSeq Peptide - NP_001308287
RefSeq Peptide - NP_001308288
RefSeq Peptide - NP_001308290
RefSeq Peptide - NP_001308291
RefSeq Peptide - NP_001308286
swissprot - Q9UHY1
swissprot - F8W6G1
swissprot - C9JDW7
swissprot - C9JHZ6
Ensembl - ENSG00000115216
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nrbp1ENSDARG00000056089Danio rerio
 NRBP1ENSGALG00000016512Gallus gallus
 Nrbp1ENSMUSG00000029148Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRBP2 / Q9NSY0 / nuclear receptor binding protein 2ENSG0000018518956
WNK1 / Q9H4A3 / WNK lysine deficient protein kinase 1ENSG0000006023729
WNK2 / Q9Y3S1 / WNK lysine deficient protein kinase 2ENSG0000016523828
WNK3 / Q9BYP7 / WNK lysine deficient protein kinase 3ENSG0000019663228
WNK4 / Q96J92 / WNK lysine deficient protein kinase 4ENSG0000012656224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IDA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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