ENSG00000186265


Homo sapiens

Features
Gene ID: ENSG00000186265
  
Biological name :BTLA
  
Synonyms : B and T lymphocyte associated / BTLA / Q7Z6A9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q13.2
Gene start: 112463968
Gene end: 112499561
  
Corresponding Affymetrix probe sets: 236226_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000333919
Ensembl peptide - ENSP00000373178
NCBI entrez gene - 151888     See in Manteia.
OMIM - 607925
RefSeq - XM_017005748
RefSeq - NM_001085357
RefSeq - NM_181780
RefSeq - XM_011512447
RefSeq Peptide - NP_001078826
RefSeq Peptide - NP_861445
swissprot - Q7Z6A9
Ensembl - ENSG00000186265
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BX897691.1ENSDARG00000105033Danio rerio
 BtlaENSMUSG00000052013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0031295 T cell costimulation TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Costimulation by the CD28 family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000177885 GRB2 / P62993 / growth factor receptor bound protein 2  / reaction / complex
 ENSG00000157873 Q92956 / TNFRSF14 / TNF receptor superfamily member 14  / complex / reaction
 ENSG00000111679 PTPN6 / P29350 / protein tyrosine phosphatase, non-receptor type 6  / reaction / complex
 ENSG00000179295 PTPN11 / Q06124 / protein tyrosine phosphatase, non-receptor type 11  / complex / reaction






 

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contact: otassy@igbmc.fr