ENSG00000186280


Homo sapiens

Features
Gene ID: ENSG00000186280
  
Biological name :KDM4D
  
Synonyms : KDM4D / lysine demethylase 4D / Q6B0I6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q21
Gene start: 94973681
Gene end: 94999518
  
Corresponding Affymetrix probe sets: 220278_at (Human Genome U133 Plus 2.0 Array)   242788_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460897
Ensembl peptide - ENSP00000482224
Ensembl peptide - ENSP00000334181
NCBI entrez gene - 55693     See in Manteia.
OMIM - 609766
RefSeq - NM_018039
RefSeq Peptide - NP_060509
swissprot - Q6B0I6
Ensembl - ENSG00000186280
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Kdm4dENSMUSG00000053914Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KDM4F / lysine demethylase 4FENSG0000025585568
KDM4E / B2RXH2 / lysine demethylase 4EENSG0000023526863
KDM4B / O94953 / lysine demethylase 4BENSG0000012766353
KDM4A / O75164 / lysine demethylase 4AENSG0000006613550
KDM4C / Q9H3R0 / lysine demethylase 4CENSG0000010707749
AL451062.3ENSG0000028498926


Protein motifs (from Interpro)
Interpro ID Name
 IPR003347  JmjC domain
 IPR003349  JmjN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0001932 regulation of protein phosphorylation IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0033169 histone H3-K9 demethylation IDA
 biological_processGO:0035563 positive regulation of chromatin binding IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071479 cellular response to ionizing radiation IMP
 biological_processGO:2001034 positive regulation of double-strand break repair via nonhomologous end joining IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0035861 site of double-strand break IDA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0032452 histone demethylase activity TAS
 molecular_functionGO:0032454 histone demethylase activity (H3-K9 specific) IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
HDMs demethylate histones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr