ENSG00000186416


Homo sapiens

Features
Gene ID: ENSG00000186416
  
Biological name :NKRF
  
Synonyms : NFKB repressing factor / NKRF / O15226
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q24
Gene start: 119588337
Gene end: 119605895
  
Corresponding Affymetrix probe sets: 205004_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442308
Ensembl peptide - ENSP00000304803
Ensembl peptide - ENSP00000360582
NCBI entrez gene - 55922     See in Manteia.
OMIM - 300440
RefSeq - XM_011531365
RefSeq - NM_001173487
RefSeq - NM_001173488
RefSeq - NM_017544
RefSeq Peptide - NP_001166958
RefSeq Peptide - NP_001166959
RefSeq Peptide - NP_060014
swissprot - O15226
swissprot - A3F769
Ensembl - ENSG00000186416
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkrfENSDARG00000100536Danio rerio
 NKRFENSGALG00000008645Gallus gallus
 NkrfENSMUSG00000044149Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NXV6 / CDKN2AIP / CDKN2A interacting proteinENSG0000016856410
Q96HQ2 / CDKN2AIPNL / CDKN2A interacting protein N-terminal likeENSG000002371901


Protein motifs (from Interpro)
Interpro ID Name
 IPR000467  G-patch domain
 IPR001374  R3H domain
 IPR014720  Double-stranded RNA-binding domain
 IPR034071  NF-kappaB-repression factor, R3H domain
 IPR036867  R3H domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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