ENSG00000186625


Homo sapiens

Features
Gene ID: ENSG00000186625
  
Biological name :KATNA1
  
Synonyms : katanin catalytic subunit A1 / KATNA1 / O75449
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q25.1
Gene start: 149594873
Gene end: 149648972
  
Corresponding Affymetrix probe sets: 205526_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398993
Ensembl peptide - ENSP00000335180
Ensembl peptide - ENSP00000356381
Ensembl peptide - ENSP00000390322
Ensembl peptide - ENSP00000335106
NCBI entrez gene - 11104     See in Manteia.
OMIM - 606696
RefSeq - XM_017010210
RefSeq - XM_005266804
RefSeq - XM_005266805
RefSeq - XM_017010207
RefSeq - XM_017010208
RefSeq - XM_017010209
RefSeq - NM_001204076
RefSeq - NM_007044
RefSeq Peptide - NP_001191005
RefSeq Peptide - NP_008975
swissprot - B7ZBC9
swissprot - O75449
swissprot - B7ZBC8
Ensembl - ENSG00000186625
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 katna1ENSDARG00000021827Danio rerio
 KATNA1ENSGALG00000012378Gallus gallus
 Katna1ENSMUSG00000019794Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BW62 / KATNAL1 / katanin catalytic subunit A1 like 1ENSG0000010278167
Q8IYT4 / KATNAL2 / katanin catalytic subunit A1 like 2ENSG0000016721634
VPS4A / Q9UN37 / vacuolar protein sorting 4 homolog AENSG0000013261233
VPS4B / O75351 / vacuolar protein sorting 4 homolog BENSG0000011954132
AC026464.4ENSG0000026091431


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR003960  ATPase, AAA-type, conserved site
 IPR015415  Vps4 oligomerisation, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028596  Katanin p60 subunit A1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051013 microtubule severing IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0097431 mitotic spindle pole IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0008568 microtubule-severing ATPase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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