ENSG00000187094


Homo sapiens

Features
Gene ID: ENSG00000187094
  
Biological name :CCK
  
Synonyms : CCK / cholecystokinin / P06307
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p22.1
Gene start: 42257825
Gene end: 42266207
  
Corresponding Affymetrix probe sets: 205827_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000335657
Ensembl peptide - ENSP00000379472
Ensembl peptide - ENSP00000409124
NCBI entrez gene - 885     See in Manteia.
OMIM - 118440
RefSeq - NM_000729
RefSeq - NM_001174138
RefSeq Peptide - NP_000720
RefSeq Peptide - NP_001167609
swissprot - P06307
swissprot - Q6FG82
Ensembl - ENSG00000187094
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cckaENSDARG00000070810Danio rerio
 CCKENSGALG00000029788Gallus gallus
 CckENSMUSG00000032532Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001651  Gastrin/cholecystokinin peptide hormone
 IPR013152  Gastrin/cholecystokinin, conserved site
 IPR015499  Cholecystokinin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IEA
 biological_processGO:0001764 neuron migration ISS
 biological_processGO:0001836 release of cytochrome c from mitochondria IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014049 positive regulation of glutamate secretion IEA
 biological_processGO:0032099 negative regulation of appetite IEA
 biological_processGO:0032461 positive regulation of protein oligomerization IEA
 biological_processGO:0042755 eating behavior ISS
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051901 positive regulation of mitochondrial depolarization IEA
 biological_processGO:0051930 regulation of sensory perception of pain IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043194 axon initial segment IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0043203 axon hillock IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005179 hormone activity TAS
 molecular_functionGO:0005184 neuropeptide hormone activity ISS


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163394 CCKAR / P32238 / cholecystokinin A receptor  / reaction / complex
 ENSG00000110148 CCKBR / P32239 / cholecystokinin B receptor  / reaction / complex






 

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