ENSG00000163394


Homo sapiens

Features
Gene ID: ENSG00000163394
  
Biological name :CCKAR
  
Synonyms : CCKAR / cholecystokinin A receptor / P32238
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p15.2
Gene start: 26481400
Gene end: 26490462
  
Corresponding Affymetrix probe sets: 211173_at (Human Genome U133 Plus 2.0 Array)   211174_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295589
NCBI entrez gene - 886     See in Manteia.
OMIM - 118444
RefSeq - NM_000730
RefSeq Peptide - NP_000721
swissprot - P32238
Ensembl - ENSG00000163394
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCKARENSDARG00000052089Danio rerio
 CCKARENSGALG00000030801Gallus gallus
 CckarENSMUSG00000029193Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCKBR / P32239 / cholecystokinin B receptorENSG0000011014850
NPFFR2 / Q9Y5X5 / neuropeptide FF receptor 2ENSG0000005629126
NPFFR1 / Q9GZQ6 / neuropeptide FF receptor 1ENSG0000014873426
HCRTR2 / O43614 / hypocretin receptor 2ENSG0000013725224
GALR2 / O43603 / galanin receptor 2ENSG0000018268724
HCRTR1 / O43613 / hypocretin receptor 1ENSG0000012176423
QRFPR / Q96P65 / pyroglutamylated RFamide peptide receptorENSG0000018686723
GALR1 / P47211 / galanin receptor 1ENSG0000016657322
GALR3 / O60755 / galanin receptor 3ENSG0000012831021
KISS1R / Q969F8 / KISS1 receptorENSG0000011601420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000596  Cholecystokinin receptor type A
 IPR009126  Cholecystokinin receptor
 IPR015276  Cholecystokinin A receptor, N-terminal
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR036472  Cholecystokinin A receptor, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007409 axonogenesis IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:0038188 cholecystokinin signaling pathway IDA
 biological_processGO:0046883 regulation of hormone secretion IBA
 biological_processGO:1901652 response to peptide IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004951 cholecystokinin receptor activity TAS
 molecular_functionGO:0017046 peptide hormone binding IPI
 molecular_functionGO:0042277 peptide binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000187094 CCK / P06307 / cholecystokinin  / reaction / complex






 

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