ENSG00000128310


Homo sapiens

Features
Gene ID: ENSG00000128310
  
Biological name :GALR3
  
Synonyms : galanin receptor 3 / GALR3 / O60755
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.1
Gene start: 37823382
Gene end: 37825495
  
Corresponding Affymetrix probe sets: 33579_i_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000249041
NCBI entrez gene - 8484     See in Manteia.
OMIM - 603692
RefSeq - NM_003614
RefSeq Peptide - NP_003605
swissprot - O60755
Ensembl - ENSG00000128310
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galr2bENSDARG00000105113Danio rerio
 GALR3ENSGALG00000012307Gallus gallus
 Galr3ENSMUSG00000114755Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GALR2 / O43603 / galanin receptor 2ENSG0000018268754
KISS1R / Q969F8 / KISS1 receptorENSG0000011601435
GALR1 / P47211 / galanin receptor 1ENSG0000016657332
NPFFR1 / Q9GZQ6 / neuropeptide FF receptor 1ENSG0000014873427
CCKAR / P32238 / cholecystokinin A receptorENSG0000016339424
CCKBR / P32239 / cholecystokinin B receptorENSG0000011014823
NPFFR2 / Q9Y5X5 / neuropeptide FF receptor 2ENSG0000005629122
QRFPR / Q96P65 / pyroglutamylated RFamide peptide receptorENSG0000018686722
HCRTR1 / O43613 / hypocretin receptor 1ENSG0000012176421
HCRTR2 / O43614 / hypocretin receptor 2ENSG0000013725221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000405  Galanin receptor family
 IPR003908  Galanin receptor 3
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IDA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007194 negative regulation of adenylate cyclase activity IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007218 neuropeptide signaling pathway TAS
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0007611 learning or memory TAS
 biological_processGO:0007631 feeding behavior TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0090663 galanin-activated signaling pathway IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0097730 non-motile cilium IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004966 galanin receptor activity TAS
 molecular_functionGO:0017046 peptide hormone binding IPI


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069482 GAL / P22466 / galanin and GMAP prepropeptide  / reaction / complex






 

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