ENSG00000182687


Homo sapiens

Features
Gene ID: ENSG00000182687
  
Biological name :GALR2
  
Synonyms : galanin receptor 2 / GALR2 / O43603
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.1
Gene start: 76074794
Gene end: 76077541
  
Corresponding Affymetrix probe sets: 211226_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000329684
NCBI entrez gene - 8811     See in Manteia.
OMIM - 603691
RefSeq - NM_003857
RefSeq Peptide - NP_003848
swissprot - O43603
Ensembl - ENSG00000182687
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galr2aENSDARG00000020853Danio rerio
 GALR2ENSGALG00000002088Gallus gallus
 Galr2ENSMUSG00000020793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GALR3 / O60755 / galanin receptor 3ENSG0000012831052
KISS1R / Q969F8 / KISS1 receptorENSG0000011601433
GALR1 / P47211 / galanin receptor 1ENSG0000016657333
CCKAR / P32238 / cholecystokinin A receptorENSG0000016339426
NPFFR1 / Q9GZQ6 / neuropeptide FF receptor 1ENSG0000014873426
CCKBR / P32239 / cholecystokinin B receptorENSG0000011014825
NPFFR2 / Q9Y5X5 / neuropeptide FF receptor 2ENSG0000005629124
HCRTR2 / O43614 / hypocretin receptor 2ENSG0000013725223
HCRTR1 / O43613 / hypocretin receptor 1ENSG0000012176422
QRFPR / Q96P65 / pyroglutamylated RFamide peptide receptorENSG0000018686719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000405  Galanin receptor family
 IPR003907  Galanin receptor 2
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007194 negative regulation of adenylate cyclase activity IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0007611 learning or memory TAS
 biological_processGO:0007631 feeding behavior TAS
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0043647 inositol phosphate metabolic process IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0090663 galanin-activated signaling pathway IDA
 biological_processGO:1902608 positive regulation of large conductance calcium-activated potassium channel activity IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004966 galanin receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017046 peptide hormone binding IPI
 molecular_functionGO:0042923 neuropeptide binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069482 GAL / P22466 / galanin and GMAP prepropeptide  / reaction / complex






 

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