ENSMUSG00000114755


Mus musculus

Features
Gene ID: ENSMUSG00000114755
  
Biological name :Galr3
  
Synonyms : Galanin receptor type 3 / Galr3 / O88853
  
Possible biological names infered from orthology : galanin receptor 3 / O60755
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 79041885
Gene end: 79043558
  
Corresponding Affymetrix probe sets: 10425223 (MoGene1.0st)   1450581_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000060517
NCBI entrez gene - 14429     See in Manteia.
MGI - MGI:1329003
RefSeq - NM_015738
RefSeq Peptide - NP_056553
swissprot - O88853
Ensembl - ENSMUSG00000114755
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galr2bENSDARG00000105113Danio rerio
 GALR3ENSGALG00000012307Gallus gallus
 GALR3ENSG00000128310Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Galr2 / O88854 / Galanin receptor type 2 / O43603* / galanin receptor 2*ENSMUSG0000002079351
Kiss1r / Q91V45 / Mus musculus KISS1 receptor (Kiss1r), transcript variant 2, mRNA. / Q969F8* / KISS1 receptor*ENSMUSG0000003577332
Galr1 / P56479 / Galanin receptor type 1 / P47211* / galanin receptor 1*ENSMUSG0000002455331
Npffr1 / neuropeptide FF receptor 1 / Q9GZQ6*ENSMUSG0000002009025
Cckar / O08786 / Cholecystokinin receptor type A / P32238* / cholecystokinin A receptor*ENSMUSG0000002919324
Npffr2 / Q924H0 / Neuropeptide FF receptor 2 / Q9Y5X5*ENSMUSG0000003552822
Qrfpr / P83861 / pyroglutamylated RFamide peptide receptor / Q96P65*ENSMUSG0000005840022
C130060K24Rik / RIKEN cDNA C130060K24 gene / QRFPR* / Q96P65* / pyroglutamylated RFamide peptide receptor*ENSMUSG0000002991721
Cckbr / P56481 / Gastrin/cholecystokinin type B receptor / P32239* / cholecystokinin B receptor*ENSMUSG0000003089821
Hcrtr2 / P58308 / Orexin receptor type 2 / O43614* / hypocretin receptor 2*ENSMUSG0000003236020
Hcrtr1 / P58307 / Orexin receptor type 1 / O43613* / hypocretin receptor 1*ENSMUSG0000002877820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000405  Galanin receptor family
 IPR003908  Galanin receptor 3
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007194 negative regulation of adenylate cyclase activity IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0090663 galanin-activated signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0097730 non-motile cilium IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004966 galanin receptor activity IBA
 molecular_functionGO:0017046 peptide hormone binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001360 abnormal social investigation "altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sdcbptm1c(KOMP)Wtsi/Sdcbp+,Tsc2tm1Tno/Tsc2+,Tg(Camk2a-cre)2Gsc/0
Genetic Background: involves: 129S4/SvJae * C57BL/6N * FVB/N

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
Show

Allelic Composition: Sdcbptm1c(KOMP)Wtsi/Sdcbp+,Tsc2tm1Tno/Tsc2+,Tg(Camk2a-cre)2Gsc/0
Genetic Background: involves: 129S4/SvJae * C57BL/6N * FVB/N

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Sdcbptm1c(KOMP)Wtsi/Sdcbp+,Tsc2tm1Tno/Tsc2+,Tg(Camk2a-cre)2Gsc/0
Genetic Background: involves: 129S4/SvJae * C57BL/6N * FVB/N

 MP:0003982 increased cholesterol level "greater than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gtf2ird1tm1Hrd/Gtf2ird1tm1Hrd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005317 increased triglyceride level "higher than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gtf2ird1tm1Hrd/Gtf2ird1tm1Hrd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024907 Gal / P47212 / Galanin peptides Galanin Galanin message-associated peptide / P22466* / galanin and GMAP prepropeptide*  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr