ENSMUSG00000035773


Mus musculus

Features
Gene ID: ENSMUSG00000035773
  
Biological name :Kiss1r
  
Synonyms : Kiss1r / Mus musculus KISS1 receptor (Kiss1r), transcript variant 2, mRNA. / Q91V45
  
Possible biological names infered from orthology : KISS1 receptor / Q969F8
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 79916971
Gene end: 79922273
  
Corresponding Affymetrix probe sets: 10364550 (MoGene1.0st)   1450493_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151936
Ensembl peptide - ENSMUSP00000040516
NCBI entrez gene - 114229     See in Manteia.
MGI - MGI:2148793
RefSeq - XM_006513080
RefSeq - NM_053244
RefSeq - XM_006513076
RefSeq - XM_006513077
RefSeq - XM_006513078
RefSeq - XM_006513079
RefSeq - NM_001359010
RefSeq Peptide - NP_001345939
RefSeq Peptide - NP_444474
swissprot - C5H7S2
swissprot - Q91V45
swissprot - B2CP06
Ensembl - ENSMUSG00000035773
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kiss1raENSDARG00000002728Danio rerio
 KISS1RENSG00000116014Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Galr3 / O88853 / Galanin receptor type 3 / O60755* / galanin receptor 3*ENSMUSG0000011475530
Galr1 / P56479 / Galanin receptor type 1 / P47211* / galanin receptor 1*ENSMUSG0000002455329
Galr2 / O88854 / Galanin receptor type 2 / O43603* / galanin receptor 2*ENSMUSG0000002079329
Hcrtr1 / P58307 / Orexin receptor type 1 / O43613* / hypocretin receptor 1*ENSMUSG0000002877824
Npffr1 / neuropeptide FF receptor 1 / Q9GZQ6*ENSMUSG0000002009023
Hcrtr2 / P58308 / Orexin receptor type 2 / O43614* / hypocretin receptor 2*ENSMUSG0000003236022
Cckar / O08786 / Cholecystokinin receptor type A / P32238* / cholecystokinin A receptor*ENSMUSG0000002919321
Qrfpr / P83861 / pyroglutamylated RFamide peptide receptor / Q96P65*ENSMUSG0000005840021
Npffr2 / Q924H0 / Neuropeptide FF receptor 2 / Q9Y5X5*ENSMUSG0000003552821
Cckbr / P56481 / Gastrin/cholecystokinin type B receptor / P32239* / cholecystokinin B receptor*ENSMUSG0000003089821
C130060K24Rik / RIKEN cDNA C130060K24 gene / QRFPR* / Q96P65* / pyroglutamylated RFamide peptide receptor*ENSMUSG0000002991719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR008103  KiSS-1 peptide receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IDA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008188 neuropeptide receptor activity ISO
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IDA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0000222 decreased neutrophil count "fewer than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0000223 decreased monocyte count "fewer than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0000662 abnormal branching of the mammary ductal tree "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0000837 abnormal hypothalamus morphology "any malformation or absence of the ventral part of the diencephalon extending from the region of the optic chiasm to the caudal border of the mammillary bodies and forming the inferior and lateral walls of the third ventricle; this region regulates the autonomic nervous system via hormone production and release" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

 MP:0000939 reduced motor neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

 MP:0001102 small superior vagus ganglion "reduced size of the upper ganglion of the vagus nerve located at the jugular foramen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0001116 small gonad "reduced size of the testis or the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001119 abnormal female reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli1tm1Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001121 uterine hypoplasia "reduced size of the uterus due to decreased cell number" [J:45065]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

 MP:0001126 abnormal ovary morphology "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Dolkem1(IMPC)J/Dolkem1(IMPC)J
Genetic Background: C57BL/6NJ-Dolkem1(IMPC)J/J

 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0001131 abnormal ovarian follicles "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001132 absent mature ovarian follicles "failure of ovarian follicle differentiation" [J:35782]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0001134 absent corpora lutea "missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0001143 constricted vaginal opening "shrunken, narrowed external vaginal opening" [J:50844]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001144 fused vaginal opening "condition in which the external vaginal opening is closed by the adherence of the epithelium of the vagina" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

 MP:0001145 abnormal male reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gli1tm1Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Dolkem1(IMPC)J/Dolkem1(IMPC)J
Genetic Background: C57BL/6NJ-Dolkem1(IMPC)J/J

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001157 small seminal gland "reduced size, compared to the norm, of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001159 absent prostate gland "missing gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66126]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Gli1tm1Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0001380 male reduced copulation without impotence "males do not initiate sexual behavior as scored by the presence of copulation plugs (not due to infertility)" [J:57125]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0001919 abnormal reproductive system physiology "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp5se-4J/Bmp5se-4J
Genetic Background: B6(Cg)-Bmp5se-4J/J

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0001927 abnormal oestrous cycle (sensu Rodentia) "failure of or aberrant timing of the sexual cycle of female animals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Npr3skm1/Npr3skm1
Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * DBA/2J

 MP:0001931 abnormal oogenesis "atypical formation or failure to form the female germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Npr3skm1/Npr3skm1
Genetic Background: involves: 129S1/SvImJ * 129X1/SvJ * DBA/2J

 MP:0001938 delayed sexual maturation "immaturity of the sexual organs at a given age" [J:61190]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0002059 abnormal seminal gland morphology "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Dolkem1(IMPC)J/Dolkem1(IMPC)J
Genetic Background: C57BL/6NJ-Dolkem1(IMPC)J/J

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dolkem1(IMPC)J/Dolkem1(IMPC)J
Genetic Background: C57BL/6NJ-Dolkem1(IMPC)J/J

 MP:0002160 abnormal reproductive system morphology "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp5se-4J/Bmp5se-4J
Genetic Background: B6(Cg)-Bmp5se-4J/J

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0002161 abnormal fertility/fecundity "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gli1tm1Alj/Gli1+,Gli2tm1Alj/Gli2tm1Alj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ccm2tm1Kwhi/Ccm2tm1.1Kwhi,Tg(Pdgfb-icre/ERT2)1Frut/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0002566 abnormal sexual interaction "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp5se-4J/Bmp5se-4J
Genetic Background: B6(Cg)-Bmp5se-4J/J

 MP:0002607 decreased basophil count "lower than average number of basophils as measured by the percent of the total number of leukocytes" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MPD:Mouse Phenome Database]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0002631 abnormal epididymis morphology "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0002636 delayed vaginal opening "the opening of the genital canal in a female occuring at a later than expected age" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0002637 small uterus "reduced size of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
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Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0002716 small preputial glands "reduced size of the sebaceous glands of the corona and neck of the glans penis" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, il:Ira Lu , Mouse Genome Informatics Curator, J:82312]
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0002773 decreased circulating luteinizing hormone level "lower than normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35132, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0002774 small prostate "reduced size of the gland in males that secretes part of the seminiferous fluid" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0002777 absent ovarian follicles "lack of the sac-like structures in the ovaries that surround the ova" [J:42612, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

 MP:0002780 decreased circulating testosterone level "less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

 MP:0002790 decreased circulating follicle stimulating hormone level "less than expected blood concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0002834 decreased heart weight "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0002965 hyperalbuminemia "blood albumin concentration above the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0003179 decreased platelet count "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0003344 mammary gland hypoplasia "decreased size of mammary gland due to decreased cell number" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

 MP:0003363 decreased circulating gonadotropin level "less than the normal blood concentration of the peptide hormones that stimulate gonadal functions such as gametogenesis and sex steroid hormone production in the ovary and the testis " [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0003379 absent sexual maturation "failure to initiate pubertal changes that result in achievement of full sexual capacity" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0003402 decreased liver weight "reduced average weight of the bile-secreting exocrine gland" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0003531 abnormal vagina development "abnormal morphogenesis of the female reproductive canal located between the uterus and the vulva" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Ccm2tm1Kwhi/Ccm2tm1.1Kwhi,Tg(Pdgfb-icre/ERT2)1Frut/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0003558 absent uterus "absence of the female muscular organ of gestation" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0003578 absent ovary "absence of the female reproductive gland containing the germ cells" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0003638 abnormal response/metabolism to endogenous compounds "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

 MP:0003642 absent seminal gland "absence of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0003795 abnormal bone structure 
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0003918 decreased kidney weight "reduced heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0003967 abnormal follicle stimulating hormone level 
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0003969 abnormal lutenizing hormone level 
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Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0004727 absent epididymis "absence of the elongated structure connected to the posterior surface of the testis, consisting of the head, body, and tail, which turns sharply on itself to become the ductus deferens (vas deferens)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0004856 decreased ovary weight "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+,Kiss1rtm1.1(cre)Uboe/Kiss1r+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0004905 decreased uterus weight "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0004910 decreased seminal gland weight "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0004929 decreased epididymis weight "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0004930 small epididymis "decrease in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0004952 increased spleen weight "greater than average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0004955 increased thymus weight "greater than average weight of the primary lymphoid organ that is required for maturation of T cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0004962 decreased prostate weight "reduction in the average weight of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0005012 decreased eosinophil count "fewer than normal eosinophil numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0005016 decreased lymphocyte number "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Lex/Kiss1r+
Genetic Background: involves: 129S4/SvJae

 MP:0005132 decreased luteinizing hormone level "lower than normal concentration of LH " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

 MP:0005148 seminal gland hypoplasia "reduction in size, usually due to a reduction in cell number, of one of the two folded, sac shaped glands that is a diverticulum of the ductus deferens" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:64337]
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Aeh/Kiss1rtm1.1Aeh,Tg(Gnrh1-cre)1Dlc/0
Genetic Background: involves: C57BL/6 * CBA

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0005181 decreased circulating estradiol level "less than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0005188 small penis "in comparison to the norm, reduced size of the organ of copulation and urination in the male" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0005189 abnormal anogenital distance "in comparison to the norm, aberration in the measure of the length of space from the genitals to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0005536 Leydig cell hypoplasia "reduced numbers of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0005567 decreased circulating total protein level "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

 MP:0006401 absent preputial gland "a lack of the sebaceous glands of the corona and neck of the glans penis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

 MP:0006415 absent testes "absence of the male reproductive glands containing the germ cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008288 abnormal adrenal cortex morphology "any structural anomaly of the thick outer layer of the adrenal gland that produces and secretes steroid hormones such as corticosterone, estrone and aldosterone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008297 retention of the x-zone "failure of the transient cortical layer juxtaposed to the medulla and the zona reticularis to degenerate after puberty in males or after pregnancy in females" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:3582592]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008869 anovulation "complete failure of ovum to be released from an ovarian follicle" [MESH:C13.351.500.056.630.050, MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008940 delayed balanopreputial separation "the separation of the prepuce from the glans penis (balanus), a result of the cornification of the balano-preputial epithelium, occurring at a later than expected age; balanopreputial separation is used as an index for the onset of male puberty and is androgen-sensitive in the rat" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1Hjn/Kiss1rtm1.1Hjn,Tg(Gnrh1-cre)35Awo/0
Genetic Background: involves: 129 * C57BL/6 * CD-1

 MP:0008948 decreased neuron number "fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]
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Allelic Composition: Gt(ROSA)26Sortm1(DTA)Riet/Gt(ROSA)26Sor+,Kiss1rtm1.1(cre)Uboe/Kiss1r+
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL

Allelic Composition: Gt(ROSA)26Sortm1(HBEGF)Awai/Gt(ROSA)26Sor+,Kiss1rtm1.1(cre)Uboe/Kiss1r+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

 MP:0008983 small vagina "decrease in the size of the female reproductive canal located between the uterus and the vulva" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

 MP:0009009 absent estrous cycle "failure of female animals to enter or progress through their sexual cycle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Lcattm1Nsa/Lcat+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

 MP:0009226 small cervix "reduced size of the lower opening of the uterus to the vagina" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

 MP:0009856 failure of ejaculation "inability to propulse semen from the genital ducts and the urethra to the exterior within a defined test period" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rGt1Stei/Kiss1rGt1Stei
Genetic Background: involves: 129S1/SvImJ * C57BL/6

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Kiss1rtm1Rla/Kiss1rtm1Rla
Genetic Background: involves: 129S1/SvImJ

 MP:0013308 decreased adrenal gland weight "reduced average weight of the pair of endocrine glands located above the kidney that are responsible for steroid hormone secretion from the cortex and neurotransmitter (such as epinephrine and norepinephrine) secretion from the medulla" [MGI:anna]
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Allelic Composition: Kiss1rtm1.1Lex/Kiss1rtm1.1Lex
Genetic Background: involves: 129S4/SvJae

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000116158 Kiss1 / Q6Y4S4 / Metastasis-suppressor KiSS-1 Metastin Kisspeptin-10 / Q15726* / KiSS-1 metastasis suppressor*  / complex / reaction






 

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