ENSG00000187605


Homo sapiens

Features
Gene ID: ENSG00000187605
  
Biological name :TET3
  
Synonyms : O43151 / TET3 / tet methylcytosine dioxygenase 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p13.1
Gene start: 73986404
Gene end: 74108176
  
Corresponding Affymetrix probe sets: 1554641_a_at (Human Genome U133 Plus 2.0 Array)   214754_at (Human Genome U133 Plus 2.0 Array)   235542_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307803
Ensembl peptide - ENSP00000386869
NCBI entrez gene - 200424     See in Manteia.
OMIM - 613555
RefSeq - XM_017003567
RefSeq - NM_001287491
RefSeq - XM_011532689
RefSeq - XM_011532690
RefSeq - XM_017003566
RefSeq - XM_005264187
RefSeq - XM_011532682
RefSeq - XM_011532683
RefSeq - XM_011532684
RefSeq - XM_011532685
RefSeq - XM_011532686
RefSeq - XM_011532687
RefSeq - XM_011532688
RefSeq Peptide - NP_001274420
swissprot - O43151
swissprot - J3KNF3
Ensembl - ENSG00000187605
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tet3ENSDARG00000062646Danio rerio
 TET3ENSGALG00000037860Gallus gallus
 Tet3ENSMUSG00000034832Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TET2 / Q6N021 / tet methylcytosine dioxygenase 2ENSG0000016876930
TET1 / Q8NFU7 / tet methylcytosine dioxygenase 1ENSG0000013833626
CXXC4 / CXXC finger protein 4ENSG000001687724
CXXC5 / Q7LFL8 / CXXC finger protein 5ENSG000001716043


Protein motifs (from Interpro)
Interpro ID Name
 IPR002857  Zinc finger, CXXC-type
 IPR024779  2OGFeDO, oxygenase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006493 protein O-linked glycosylation IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0044727 DNA demethylation of male pronucleus IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0080111 DNA demethylation IEA
 biological_processGO:0080182 histone H3-K4 trimethylation IMP
 cellular_componentGO:0001939 female pronucleus IEA
 cellular_componentGO:0001940 male pronucleus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA
 molecular_functionGO:0070579 methylcytosine dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
TET1,2,3 and TDG demethylate DNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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