ENSMUSG00000034832


Mus musculus

Features
Gene ID: ENSMUSG00000034832
  
Biological name :Tet3
  
Synonyms : Mus musculus tet methylcytosine dioxygenase 3 (Tet3), transcript variant 1, mRNA. / Q8BG87 / Tet3
  
Possible biological names infered from orthology : O43151 / tet methylcytosine dioxygenase 3
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: C3
Gene start: 83362373
Gene end: 83459084
  
Corresponding Affymetrix probe sets: 10545682 (MoGene1.0st)   10545692 (MoGene1.0st)   1439324_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000087049
Ensembl peptide - ENSMUSP00000139630
Ensembl peptide - ENSMUSP00000139679
NCBI entrez gene - 194388     See in Manteia.
MGI - MGI:2446229
RefSeq - XM_017321465
RefSeq - NM_001347313
RefSeq - NM_183138
RefSeq - XM_006505773
RefSeq - XM_006505775
RefSeq - XM_006505776
RefSeq - XM_006505777
RefSeq Peptide - NP_001334242
RefSeq Peptide - NP_898961
swissprot - Q8BG87
swissprot - A0A087WP90
Ensembl - ENSMUSG00000034832
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tet3ENSDARG00000062646Danio rerio
 TET3ENSGALG00000037860Gallus gallus
 TET3ENSG00000187605Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tet2 / Q4JK59 / Mus musculus tet methylcytosine dioxygenase 2 (Tet2), transcript variant 2, mRNA. / Q6N021* / tet methylcytosine dioxygenase 2*ENSMUSG0000004094325
Tet1 / Q3URK3 / tet methylcytosine dioxygenase 1 / Q8NFU7*ENSMUSG0000004714625
Cxxc4 / Q6NXI8 / CXXC-type zinc finger protein 4 / CXXC finger protein 4*ENSMUSG000000443654
Cxxc5 / Q91WA4 / Mus musculus CXXC finger 5 (Cxxc5), transcript variant 2, mRNA. / Q7LFL8* / CXXC finger protein 5*ENSMUSG000000466683


Protein motifs (from Interpro)
Interpro ID Name
 IPR002857  Zinc finger, CXXC-type
 IPR024779  2OGFeDO, oxygenase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006493 protein O-linked glycosylation IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0035511 oxidative DNA demethylation TAS
 biological_processGO:0044727 DNA demethylation of male pronucleus IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0080111 DNA demethylation IDA
 biological_processGO:0080182 histone H3-K4 trimethylation IEA
 cellular_componentGO:0001939 female pronucleus IDA
 cellular_componentGO:0001940 male pronucleus IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA
 molecular_functionGO:0070579 methylcytosine dioxygenase activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Juntm4Wag/Juntm4Wag,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

 MP:0003718 maternal effect "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Juntm4Wag/Juntm4Wag,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

Allelic Composition: Tet3tm1.1Gxu/Tet3tm1.2Gxu,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129 * C57BL/6J * FVB/N * SJL

 MP:0008877 abnormal DNA methylation "any anomaly in the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine of DNA" [GO:0006306]
Show

Allelic Composition: Juntm4Wag/Juntm4Wag,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL

Allelic Composition: Tet3tm1.1Gxu/Tet3tm1.2Gxu,Tg(Zp3-cre)3Mrt/0
Genetic Background: involves: 129 * C57BL/6J * FVB/N * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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