ENSG00000187735


Homo sapiens

Features
Gene ID: ENSG00000187735
  
Biological name :TCEA1
  
Synonyms : P23193 / TCEA1 / transcription elongation factor A1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q11.23
Gene start: 53966552
Gene end: 54022529
  
Corresponding Affymetrix probe sets: 1566207_at (Human Genome U133 Plus 2.0 Array)   1566208_at (Human Genome U133 Plus 2.0 Array)   216241_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395483
Ensembl peptide - ENSP00000428370
Ensembl peptide - ENSP00000492551
Ensembl peptide - ENSP00000492389
Ensembl peptide - ENSP00000491445
Ensembl peptide - ENSP00000491370
Ensembl peptide - ENSP00000430450
Ensembl peptide - ENSP00000429192
Ensembl peptide - ENSP00000429182
Ensembl peptide - ENSP00000428868
Ensembl peptide - ENSP00000428426
NCBI entrez gene - 6917     See in Manteia.
OMIM - 601425
RefSeq - NM_201437
RefSeq - NM_006756
RefSeq - XM_006716467
RefSeq - XM_011517578
RefSeq Peptide - NP_006747
RefSeq Peptide - NP_958845
swissprot - A0A1W2PRL9
swissprot - A0A1W2PPZ5
swissprot - E5RK46
swissprot - P23193
swissprot - A0A1W2PPV7
swissprot - E5RJ93
swissprot - E5RIS7
swissprot - E5RFI1
swissprot - B7Z4S1
swissprot - A0A1W2PS15
Ensembl - ENSG00000187735
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tcea1ENSDARG00000003531Danio rerio
 TCEA1ENSGALG00000015274Gallus gallus
 Tcea1ENSMUSG00000033813Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TCEA2 / Q15560 / transcription elongation factor A2ENSG0000017170366
TCEA3 / O75764 / transcription elongation factor A3ENSG0000020421959
Q8N8B7 / TCEANC / transcription elongation factor A N-terminal and central domain containingENSG0000017689630


Protein motifs (from Interpro)
Interpro ID Name
 IPR001222  Zinc finger, TFIIS-type
 IPR003617  Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
 IPR003618  Transcription elongation factor S-II, central domain
 IPR006289  Transcription elongation factor, TFIIS
 IPR017923  Transcription factor IIS, N-terminal
 IPR035100  Transcription elongation factor, IIS-type
 IPR035441  TFIIS/LEDGF domain superfamily
 IPR036575  Transcription elongation factor S-II, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:1901919 positive regulation of exoribonuclease activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005669 transcription factor TFIID complex IDA
 cellular_componentGO:0005730 nucleolus IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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