ENSG00000187908


Homo sapiens

Features
Gene ID: ENSG00000187908
  
Biological name :DMBT1
  
Synonyms : deleted in malignant brain tumors 1 / DMBT1 / Q9UGM3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.13
Gene start: 122560665
Gene end: 122643736
  
Corresponding Affymetrix probe sets: 208250_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357952
Ensembl peptide - ENSP00000327747
Ensembl peptide - ENSP00000342210
Ensembl peptide - ENSP00000343175
Ensembl peptide - ENSP00000484603
Ensembl peptide - ENSP00000357905
Ensembl peptide - ENSP00000357951
NCBI entrez gene - 1755     See in Manteia.
OMIM - 601969
RefSeq - XM_017015798
RefSeq - NM_001320644
RefSeq - NM_004406
RefSeq - NM_007329
RefSeq - NM_017579
RefSeq - XM_011539410
RefSeq - XM_011539411
RefSeq - XM_011539413
RefSeq - XM_011539414
RefSeq - XM_011539415
RefSeq - XM_006717660
RefSeq - XM_006717665
RefSeq - XM_011539388
RefSeq - XM_011539389
RefSeq - XM_011539390
RefSeq - XM_011539391
RefSeq - XM_011539392
RefSeq - XM_011539393
RefSeq - XM_011539394
RefSeq - XM_011539395
RefSeq - XM_011539396
RefSeq - XM_011539398
RefSeq - XM_011539399
RefSeq - XM_011539400
RefSeq - XM_011539401
RefSeq - XM_011539402
RefSeq - XM_011539403
RefSeq - XM_011539405
RefSeq - XM_011539407
RefSeq - XM_011539408
RefSeq - XM_011539409
RefSeq Peptide - NP_004397
RefSeq Peptide - NP_015568
RefSeq Peptide - NP_060049
RefSeq Peptide - NP_001307573
swissprot - Q9UGM3
Ensembl - ENSG00000187908
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000038396Gallus gallus
 Dmbt1ENSMUSG00000047517Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NR16 / CD163L1 / CD163 molecule like 1ENSG0000017767521
CD163 / Q86VB7 / CD163 moleculeENSG0000017757520
SSC5D / A1L4H1 / scavenger receptor cysteine rich family member with 5 domainsENSG0000017995416
Q4G0T1 / SCART1 / scavenger receptor family member expressed on T cells 1ENSG0000021427914
SSC4D / Q8WTU2 / scavenger receptor cysteine rich family member with 4 domainsENSG0000014670011
P56730 / PRSS12 / serine protease 12ENSG0000016409911
CD5L / O43866 / CD5 molecule likeENSG000000737546


Protein motifs (from Interpro)
Interpro ID Name
 IPR000859  CUB domain
 IPR001190  SRCR domain
 IPR001507  Zona pellucida domain
 IPR017448  SRCR-like domain
 IPR017977  Zona pellucida domain, conserved site
 IPR035914  Spermadhesin, CUB domain superfamily
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002221 pattern recognition receptor signaling pathway IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030855 epithelial cell differentiation TAS
 biological_processGO:0043152 induction of bacterial agglutination TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0050829 defense response to Gram-negative bacterium ISS
 biological_processGO:0050830 defense response to Gram-positive bacterium ISS
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane ISS
 cellular_componentGO:0030670 phagocytic vesicle membrane IDA
 cellular_componentGO:0042589 zymogen granule membrane ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005044 scavenger receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008329 signaling pattern recognition receptor activity TAS
 molecular_functionGO:0035375 zymogen binding ISS
 molecular_functionGO:0048306 calcium-dependent protein binding TAS


Pathways (from Reactome)
Pathway description
Surfactant metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000185303 Q8IWL1 / SFTPA2 / surfactant protein A2  / reaction / complex
 ENSG00000133661 SFTPD / P35247 / surfactant protein D  / complex / reaction
 ENSG00000122852 Q8IWL2 / SFTPA1 / surfactant protein A1  / complex / reaction
 ENSG00000229415 SFTA3 / P0C7M3 / surfactant associated 3  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr