ENSG00000196535


Homo sapiens

Features
Gene ID: ENSG00000196535
  
Biological name :MYO18A
  
Synonyms : MYO18A / myosin XVIIIA / Q92614
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q11.2
Gene start: 29071124
Gene end: 29180412
  
Corresponding Affymetrix probe sets: 202039_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000435932
Ensembl peptide - ENSP00000490952
Ensembl peptide - ENSP00000490367
Ensembl peptide - ENSP00000486682
Ensembl peptide - ENSP00000465542
Ensembl peptide - ENSP00000437073
Ensembl peptide - ENSP00000436660
Ensembl peptide - ENSP00000434228
Ensembl peptide - ENSP00000434817
NCBI entrez gene - 399687     See in Manteia.
OMIM - 610067
RefSeq - NM_078471
RefSeq - NM_203318
RefSeq - NM_001346768
RefSeq - NM_001346767
RefSeq Peptide - NP_510880
RefSeq Peptide - NP_976063
RefSeq Peptide - NP_001333696
RefSeq Peptide - NP_001333697
swissprot - Q92614
swissprot - A0A1B0GWJ6
swissprot - A0A1B0GV45
swissprot - A0A0D9SFK2
swissprot - A0A024QZ63
swissprot - H0YEV9
swissprot - K7EKB3
swissprot - E9PN42
Ensembl - ENSG00000196535
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myo18aaENSDARG00000075752Danio rerio
 myo18abENSDARG00000061862Danio rerio
 MYO18AENSGALG00000003741Gallus gallus
 Myo18aENSMUSG00000000631Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYO18B / Q8IUG5 / myosin XVIIIBENSG0000013345441


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001478  PDZ domain
 IPR001609  Myosin head, motor domain
 IPR002928  Myosin tail
 IPR020587  DNA recombination and repair protein RecA, monomer-monomer interface
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031244  Unconventional myosin-XVIIIa
 IPR036034  PDZ superfamily
 IPR036064  Class XVIII myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006259 DNA metabolic process IEA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0031032 actomyosin structure organization IMP
 biological_processGO:0043030 regulation of macrophage activation IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0048194 Golgi vesicle budding IMP
 biological_processGO:0050714 positive regulation of protein secretion IMP
 biological_processGO:0090161 Golgi ribbon formation IMP
 biological_processGO:0090164 asymmetric Golgi ribbon formation IMP
 biological_processGO:1903028 positive regulation of opsonization IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0042641 actomyosin IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0043531 ADP binding IDA
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Signaling by cytosolic FGFR1 fusion mutants
Signaling by FGFR1 in disease


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000196535 MYO18A / Q92614 / myosin XVIIIA  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr