ENSG00000196689


Homo sapiens

Features
Gene ID: ENSG00000196689
  
Biological name :TRPV1
  
Synonyms : Q8NER1 / transient receptor potential cation channel subfamily V member 1 / TRPV1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 3565444
Gene end: 3609411
  
Corresponding Affymetrix probe sets: 219632_s_at (Human Genome U133 Plus 2.0 Array)   219712_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000409627
Ensembl peptide - ENSP00000459042
Ensembl peptide - ENSP00000461007
Ensembl peptide - ENSP00000459962
Ensembl peptide - ENSP00000311692
Ensembl peptide - ENSP00000382659
Ensembl peptide - ENSP00000382661
NCBI entrez gene - 7442     See in Manteia.
OMIM - 602076
RefSeq - NM_080704
RefSeq - NM_080705
RefSeq - NM_080706
RefSeq - NM_018727
RefSeq Peptide - NP_061197
RefSeq Peptide - NP_542436
RefSeq Peptide - NP_542437
RefSeq Peptide - NP_542435
swissprot - Q8NER1
swissprot - E7EQ78
swissprot - I3L1R6
swissprot - E7ESJ2
Ensembl - ENSG00000196689
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trpv1ENSDARG00000059883Danio rerio
 TRPV1ENSGALG00000004649Gallus gallus
 Trpv1ENSMUSG00000005952Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRPV4 / Q9HBA0 / transient receptor potential cation channel subfamily V member 4ENSG0000011119944
TRPV2 / Q9Y5S1 / transient receptor potential cation channel subfamily V member 2ENSG0000018768841
TRPV3 / Q8NET8 / transient receptor potential cation channel subfamily V member 3ENSG0000016772336
TRPV6 / Q9H1D0 / transient receptor potential cation channel subfamily V member 6ENSG0000016512525
TRPV5 / Q9NQA5 / transient receptor potential cation channel subfamily V member 5ENSG0000012741223


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR004729  Transient receptor potential channel
 IPR005821  Ion transport domain
 IPR008347  Transient receptor potential channel, vanilloid 1-4
 IPR020683  Ankyrin repeat-containing domain
 IPR024862  Transient receptor potential cation channel subfamily V
 IPR024863  Transient receptor potential cation channel subfamily V member 1
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001659 temperature homeostasis IEA
 biological_processGO:0001660 fever generation IEA
 biological_processGO:0001774 microglial cell activation IEA
 biological_processGO:0002024 diet induced thermogenesis IEA
 biological_processGO:0002790 peptide secretion IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007635 chemosensory behavior TAS
 biological_processGO:0009268 response to pH IEA
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0010243 response to organonitrogen compound IEA
 biological_processGO:0014047 glutamate secretion IEA
 biological_processGO:0014832 urinary bladder smooth muscle contraction IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034605 cellular response to heat IDA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0048265 response to pain IEA
 biological_processGO:0048266 behavioral response to pain IEA
 biological_processGO:0050954 sensory perception of mechanical stimulus IEA
 biological_processGO:0050955 thermoception IDA
 biological_processGO:0050960 detection of temperature stimulus involved in thermoception IEA
 biological_processGO:0050965 detection of temperature stimulus involved in sensory perception of pain IEA
 biological_processGO:0050968 detection of chemical stimulus involved in sensory perception of pain IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051289 protein homotetramerization ISS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060083 smooth muscle contraction involved in micturition IEA
 biological_processGO:0060454 positive regulation of gastric acid secretion IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0070588 calcium ion transmembrane transport TAS
 biological_processGO:0071312 cellular response to alkaloid ISS
 biological_processGO:0071318 cellular response to ATP ISS
 biological_processGO:0071345 cellular response to cytokine stimulus IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:0071468 cellular response to acidic pH IDA
 biological_processGO:0071502 cellular response to temperature stimulus IEA
 biological_processGO:0090212 negative regulation of establishment of blood-brain barrier IEA
 biological_processGO:0098703 calcium ion import across plasma membrane IDA
 biological_processGO:1901594 response to capsazepine ISS
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031226 intrinsic component of plasma membrane ISS
 cellular_componentGO:0032591 dendritic spine membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity ISS
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IDA
 molecular_functionGO:0005231 excitatory extracellular ligand-gated ion channel activity ISS
 molecular_functionGO:0005261 cation channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding ISS
 molecular_functionGO:0005524 ATP binding ISS
 molecular_functionGO:0008324 cation transmembrane transporter activity IEA
 molecular_functionGO:0015276 ligand-gated ion channel activity IEA
 molecular_functionGO:0015278 calcium-release channel activity ISS
 molecular_functionGO:0017081 chloride channel regulator activity IEA
 molecular_functionGO:0035091 phosphatidylinositol binding ISS
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051219 phosphoprotein binding IPI
 molecular_functionGO:0097603 temperature-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
TRP channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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