ENSG00000198887


Homo sapiens

Features
Gene ID: ENSG00000198887
  
Biological name :SMC5
  
Synonyms : Q8IY18 / SMC5 / structural maintenance of chromosomes 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q21.12
Gene start: 70258962
Gene end: 70354888
  
Corresponding Affymetrix probe sets: 212926_at (Human Genome U133 Plus 2.0 Array)   212927_at (Human Genome U133 Plus 2.0 Array)   237725_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354957
NCBI entrez gene - 23137     See in Manteia.
OMIM - 609386
RefSeq - XM_017014510
RefSeq - NM_015110
RefSeq - XM_017014508
RefSeq - XM_017014509
RefSeq - XM_005251837
RefSeq - XM_005251838
RefSeq - XM_005251839
RefSeq - XM_017014507
RefSeq Peptide - NP_055925
swissprot - Q8IY18
Ensembl - ENSG00000198887
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smc5ENSDARG00000044282Danio rerio
 SMC5ENSGALG00000015118Gallus gallus
 Smc5ENSMUSG00000024943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003395  RecF/RecN/SMC, N-terminal
 IPR027131  Structural maintenance of chromosomes protein 5
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000722 telomere maintenance via recombination IMP
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007062 sister chromatid cohesion IEA
 biological_processGO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051984 positive regulation of chromosome segregation IMP
 biological_processGO:0090398 cellular senescence IMP
 cellular_componentGO:0000781 chromosome, telomeric region IEA
 cellular_componentGO:0000803 sex chromosome IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0030915 Smc5-Smc6 complex IDA
 cellular_componentGO:0035061 interchromatin granule IDA
 cellular_componentGO:0035861 site of double-strand break IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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