ENSG00000204193


Homo sapiens

Features
Gene ID: ENSG00000204193
  
Biological name :TXNDC8
  
Synonyms : Q6A555 / thioredoxin domain containing 8 / TXNDC8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q31.3
Gene start: 110303521
Gene end: 110337884
  
Corresponding Affymetrix probe sets: 1564386_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363635
Ensembl peptide - ENSP00000408768
Ensembl peptide - ENSP00000363631
Ensembl peptide - ENSP00000363634
NCBI entrez gene - 255220     See in Manteia.
OMIM - 617789
RefSeq - XM_017014584
RefSeq - NM_001286947
RefSeq - XM_017014579
RefSeq - XM_017014580
RefSeq - XM_017014581
RefSeq - XM_017014582
RefSeq - XM_017014583
RefSeq - NM_001003936
RefSeq - NM_001286946
RefSeq Peptide - NP_001273876
RefSeq Peptide - NP_001003936
RefSeq Peptide - NP_001273875
swissprot - B7ZME0
swissprot - Q6A555
swissprot - A9Z1W9
Ensembl - ENSG00000204193
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txnENSDARG00000044125Danio rerio
 zgc:56493ENSDARG00000031435Danio rerio
 Q69AB2ENSMUSG00000038709Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TXN / P10599 / thioredoxinENSG0000013681038
Q86VQ3 / TXNDC2 / thioredoxin domain containing 2ENSG0000016845434
TXNL1 / O43396 / thioredoxin like 1ENSG0000009116430


Protein motifs (from Interpro)
Interpro ID Name
 IPR005746  Thioredoxin
 IPR013766  Thioredoxin domain
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001675 acrosome assembly IEA
 biological_processGO:0006662 glycerol ether metabolic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0034599 cellular response to oxidative stress IBA
 biological_processGO:0045454 cell redox homeostasis IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0036126 sperm flagellum IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IBA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IEA
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IBA
 molecular_functionGO:0047134 protein-disulfide reductase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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