ENSG00000168454


Homo sapiens

Features
Gene ID: ENSG00000168454
  
Biological name :TXNDC2
  
Synonyms : Q86VQ3 / thioredoxin domain containing 2 / TXNDC2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: p11.22
Gene start: 9885726
Gene end: 9889275
  
Corresponding Affymetrix probe sets: 1552657_a_at (Human Genome U133 Plus 2.0 Array)   224168_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304908
Ensembl peptide - ENSP00000437393
Ensembl peptide - ENSP00000464677
Ensembl peptide - ENSP00000483261
Ensembl peptide - ENSP00000350419
NCBI entrez gene - 84203     See in Manteia.
OMIM - 617790
RefSeq - XM_017026041
RefSeq - NM_001098529
RefSeq - NM_032243
RefSeq Peptide - NP_001091999
RefSeq Peptide - NP_115619
swissprot - Q86VQ3
swissprot - A0A140VJY8
swissprot - F5H6S7
swissprot - J3QSG5
Ensembl - ENSG00000168454
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txnENSDARG00000044125Danio rerio
 zgc:56493ENSDARG00000031435Danio rerio
 TXNENSGALG00000015704Gallus gallus
 Txndc2ENSMUSG00000050612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TXN / P10599 / thioredoxinENSG0000013681011
TXNL1 / O43396 / thioredoxin like 1ENSG000000911647
Q6A555 / TXNDC8 / thioredoxin domain containing 8ENSG000002041937


Protein motifs (from Interpro)
Interpro ID Name
 IPR005746  Thioredoxin
 IPR013766  Thioredoxin domain
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006662 glycerol ether metabolic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis NAS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0034599 cellular response to oxidative stress IBA
 biological_processGO:0045454 cell redox homeostasis IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity ISS
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IBA
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IBA
 molecular_functionGO:0047134 protein-disulfide reductase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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