ENSG00000204304


Homo sapiens

Features
Gene ID: ENSG00000204304
  
Biological name :PBX2
  
Synonyms : P40425 / PBX2 / PBX homeobox 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.32
Gene start: 32184741
Gene end: 32190186
  
Corresponding Affymetrix probe sets: 202875_s_at (Human Genome U133 Plus 2.0 Array)   202876_s_at (Human Genome U133 Plus 2.0 Array)   211096_at (Human Genome U133 Plus 2.0 Array)   211097_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364190
NCBI entrez gene - 5089     See in Manteia.
OMIM - 176311
RefSeq - NM_002586
RefSeq Peptide - NP_002577
swissprot - A0A024RCR3
swissprot - P40425
Ensembl - ENSG00000204304
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pbx2ENSDARG00000019717Danio rerio
 Pbx2ENSMUSG00000034673Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PBX3 / P40426 / PBX homeobox 3ENSG0000016708175
PBX1 / P40424 / PBX homeobox 1ENSG0000018563074
PBX4 / Q9BYU1 / PBX homeobox 4ENSG0000010571759


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR005542  PBX
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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