ENSG00000167081


Homo sapiens

Features
Gene ID: ENSG00000167081
  
Biological name :PBX3
  
Synonyms : P40426 / PBX3 / PBX homeobox 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q33.3
Gene start: 125747345
Gene end: 125967377
  
Corresponding Affymetrix probe sets: 204082_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475679
Ensembl peptide - ENSP00000387456
Ensembl peptide - ENSP00000397903
Ensembl peptide - ENSP00000341990
Ensembl peptide - ENSP00000362581
Ensembl peptide - ENSP00000362586
Ensembl peptide - ENSP00000362588
Ensembl peptide - ENSP00000362591
NCBI entrez gene - 5090     See in Manteia.
OMIM - 176312
RefSeq - XM_017014786
RefSeq - NM_001134778
RefSeq - NM_001330782
RefSeq - NM_006195
RefSeq - XM_006717130
RefSeq - XM_006717131
RefSeq - XM_006717132
RefSeq - XM_006717133
RefSeq - XM_011518755
RefSeq Peptide - NP_001317711
RefSeq Peptide - NP_006186
RefSeq Peptide - NP_001128250
swissprot - H0Y5D0
swissprot - H3BLX0
swissprot - P40426
swissprot - Q5JS98
swissprot - U3KQA2
Ensembl - ENSG00000167081
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pbx3aENSDARG00000089262Danio rerio
 pbx3bENSDARG00000013615Danio rerio
 PBX3ENSGALG00000000972Gallus gallus
 Pbx3ENSMUSG00000038718Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PBX1 / P40424 / PBX homeobox 1ENSG0000018563083
PBX2 / P40425 / PBX homeobox 2ENSG0000020430474
PBX4 / Q9BYU1 / PBX homeobox 4ENSG0000010571759


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR005542  PBX
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002087 regulation of respiratory gaseous exchange by neurological system process IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007387 anterior compartment pattern formation TAS
 biological_processGO:0007388 posterior compartment specification TAS
 biological_processGO:0007585 respiratory gaseous exchange IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0021516 dorsal spinal cord development IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048666 neuron development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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