ENSG00000204392


Homo sapiens

Features
Gene ID: ENSG00000204392
  
Biological name :LSM2
  
Synonyms : LSM2 / LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated / Q9Y333
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.33
Gene start: 31797396
Gene end: 31806984
  
Corresponding Affymetrix probe sets: 209449_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364813
NCBI entrez gene - 57819     See in Manteia.
OMIM - 607282
RefSeq - NM_021177
RefSeq Peptide - NP_067000
swissprot - Q9Y333
Ensembl - ENSG00000204392
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smx5ENSDARG00000103066Danio rerio
 smx5ENSDARG00000070867Danio rerio
 Lsm2ENSMUSG00000007050Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001163  LSM domain, eukaryotic/archaea-type
 IPR010920  LSM domain superfamily
 IPR016654  U6 snRNA-associated Sm-like protein LSm2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay TAS
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005688 U6 snRNP IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0046540 U4/U6 x U5 tri-snRNP complex IBA
 cellular_componentGO:0071011 precatalytic spliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 cellular_componentGO:1990726 Lsm1-7-Pat1 complex IBA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017070 U6 snRNA binding NAS
 molecular_functionGO:0017160 Ral GTPase binding IPI


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr