ENSG00000206527


Homo sapiens

Features
Gene ID: ENSG00000206527
  
Biological name :HACD2
  
Synonyms : 3-hydroxyacyl-CoA dehydratase 2 / HACD2 / Q6Y1H2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q21.1
Gene start: 123490820
Gene end: 123585185
  
Corresponding Affymetrix probe sets: 212640_at (Human Genome U133 Plus 2.0 Array)   227741_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419237
Ensembl peptide - ENSP00000373153
Ensembl peptide - ENSP00000417567
NCBI entrez gene - 201562     See in Manteia.
OMIM - 615939
RefSeq - NM_001329786
RefSeq - NM_001329787
RefSeq - NM_198402
RefSeq Peptide - NP_940684
RefSeq Peptide - NP_001316715
RefSeq Peptide - NP_001316716
swissprot - Q6Y1H2
swissprot - H7C4K8
swissprot - C9JWG1
Ensembl - ENSG00000206527
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR376779.1ENSDARG00000109760Danio rerio
 hacd2ENSDARG00000014806Danio rerio
 HACD2ENSGALG00000011704Gallus gallus
 Hacd2ENSMUSG00000035376Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HACD1 / B0YJ81 / 3-hydroxyacyl-CoA dehydratase 1ENSG0000016599657
HACD3 / Q9P035 / 3-hydroxyacyl-CoA dehydratase 3ENSG0000007469625
HACD4 / Q5VWC8 / 3-hydroxyacyl-CoA dehydratase 4ENSG0000018892121


Protein motifs (from Interpro)
Interpro ID Name
 IPR007482  Protein-tyrosine phosphatase-like, PTPLA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process IGI
 biological_processGO:0030497 fatty acid elongation IDA
 biological_processGO:0035338 long-chain fatty-acyl-CoA biosynthetic process TAS
 biological_processGO:0042761 very long-chain fatty acid biosynthetic process IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0018812 3-hydroxyacyl-CoA dehydratase activity IDA
 molecular_functionGO:0019899 enzyme binding IDA
 molecular_functionGO:0080023 3R-hydroxyacyl-CoA dehydratase activity EXP
 molecular_functionGO:0102158 very-long-chain 3-hydroxyacyl-CoA dehydratase activity IEA
 molecular_functionGO:0102343 3-hydroxy-arachidoyl-CoA dehydratase activity IEA
 molecular_functionGO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity IEA
 molecular_functionGO:0102345 3-hydroxy-lignoceroyl-CoA dehydratase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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