ENSG00000188921


Homo sapiens

Features
Gene ID: ENSG00000188921
  
Biological name :HACD4
  
Synonyms : 3-hydroxyacyl-CoA dehydratase 4 / HACD4 / Q5VWC8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p21.3
Gene start: 20999515
Gene end: 21031636
  
Corresponding Affymetrix probe sets: 236939_at (Human Genome U133 Plus 2.0 Array)   244050_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419503
NCBI entrez gene - 401494     See in Manteia.
OMIM - 615941
RefSeq - NM_001321903
RefSeq - XM_017014714
RefSeq - NM_001010915
RefSeq - NM_001321883
RefSeq - XM_017014713
RefSeq Peptide - NP_001308832
RefSeq Peptide - NP_001010915
RefSeq Peptide - NP_001308812
swissprot - Q5VWC8
Ensembl - ENSG00000188921
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HACD4ENSDARG00000102221Danio rerio
 HACD4ENSGALG00000028142Gallus gallus
 Hacd4ENSMUSG00000028497Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HACD3 / Q9P035 / 3-hydroxyacyl-CoA dehydratase 3ENSG0000007469640
HACD2 / Q6Y1H2 / 3-hydroxyacyl-CoA dehydratase 2ENSG0000020652723
HACD1 / B0YJ81 / 3-hydroxyacyl-CoA dehydratase 1ENSG0000016599621


Protein motifs (from Interpro)
Interpro ID Name
 IPR007482  Protein-tyrosine phosphatase-like, PTPLA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process IBA
 biological_processGO:0030497 fatty acid elongation IDA
 biological_processGO:0042761 very long-chain fatty acid biosynthetic process IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IBA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0018812 3-hydroxyacyl-CoA dehydratase activity IDA
 molecular_functionGO:0019899 enzyme binding IDA
 molecular_functionGO:0102158 very-long-chain 3-hydroxyacyl-CoA dehydratase activity IEA
 molecular_functionGO:0102343 3-hydroxy-arachidoyl-CoA dehydratase activity IEA
 molecular_functionGO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity IEA
 molecular_functionGO:0102345 3-hydroxy-lignoceroyl-CoA dehydratase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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