ENSG00000213977


Homo sapiens

Features
Gene ID: ENSG00000213977
  
Biological name :TAX1BP3
  
Synonyms : O14907 / Tax1 binding protein 3 / TAX1BP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.2
Gene start: 3662896
Gene end: 3668682
  
Corresponding Affymetrix probe sets: 209154_at (Human Genome U133 Plus 2.0 Array)   215464_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484776
Ensembl peptide - ENSP00000225525
NCBI entrez gene - 30851     See in Manteia.
OMIM - 616484
RefSeq - NM_001204698
RefSeq - NM_014604
RefSeq Peptide - NP_001191627
RefSeq Peptide - NP_055419
swissprot - O14907
swissprot - A0A087X282
Ensembl - ENSG00000213977
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tax1bp3ENSDARG00000059177Danio rerio
 TAX1BP3ENSGALG00000004618Gallus gallus
 Q9DBG9ENSMUSG00000040158Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR017268  Tax1-binding protein 3
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007266 Rho protein signal transduction IDA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0090630 activation of GTPase activity IDA
 biological_processGO:2000009 negative regulation of protein localization to cell surface IDA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Rhotekin and Rhophilins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067560 RHOA / P61586 / ras homolog family member A  / reaction / complex
 ENSG00000114993 RTKN / Q9BST9 / rhotekin  / reaction / complex






 

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