ENSG00000213999


Homo sapiens

Features
Gene ID: ENSG00000213999
  
Biological name :MEF2B
  
Synonyms : MEF2B / myocyte enhancer factor 2B / Q02080
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 19145568
Gene end: 19170289
  
Corresponding Affymetrix probe sets: 205124_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000386374
Ensembl peptide - ENSP00000402154
Ensembl peptide - ENSP00000386784
Ensembl peptide - ENSP00000386480
NCBI entrez gene - 100271849     See in Manteia.
OMIM - 600661
RefSeq - NM_001145785
RefSeq Peptide - NP_001139257
swissprot - A0A024R7K5
swissprot - C9J4J4
swissprot - Q02080
swissprot - B8ZZJ5
swissprot - B3KQ23
Ensembl - ENSG00000213999
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mef2bENSDARG00000093170Danio rerio
 ENSGALG00000037558Gallus gallus
 Mef2bENSMUSG00000079033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BORCS8-MEF2B / BORCS8-MEF2B readthroughENSG0000006448973
MEF2D / Q14814 / myocyte enhancer factor 2DENSG0000011660441
MEF2A / Q02078 / myocyte enhancer factor 2AENSG0000006830539
MEF2C / Q06413 / myocyte enhancer factor 2CENSG0000008118939


Protein motifs (from Interpro)
Interpro ID Name
 IPR002100  Transcription factor, MADS-box
 IPR033896  MADS MEF2-like
 IPR036879  Transcription factor, MADS-box superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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