ENSG00000240682


Homo sapiens

Features
Gene ID: ENSG00000240682
  
Biological name :ISY1
  
Synonyms : ISY1 / ISY1 splicing factor homolog / Q9ULR0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q21.3
Gene start: 129127415
Gene end: 129161293
  
Corresponding Affymetrix probe sets: 223428_s_at (Human Genome U133 Plus 2.0 Array)   223429_x_at (Human Genome U133 Plus 2.0 Array)   223831_x_at (Human Genome U133 Plus 2.0 Array)   232142_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376970
Ensembl peptide - ENSP00000426416
Ensembl peptide - ENSP00000422403
Ensembl peptide - ENSP00000376973
Ensembl peptide - ENSP00000273541
NCBI entrez gene - 57461     See in Manteia.
OMIM - 612764
RefSeq - NM_020701
RefSeq - NM_001199469
RefSeq Peptide - NP_001186398
RefSeq Peptide - NP_065752
swissprot - Q9ULR0
swissprot - A8MVI5
swissprot - H0YA89
swissprot - D6RC18
Ensembl - ENSG00000240682
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 isy1ENSDARG00000063466Danio rerio
 ENSGALG00000005012Gallus gallus
 Isy1ENSMUSG00000030056Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ISY1-RAB43 / ISY1-RAB43 readthroughENSG0000026179692


Protein motifs (from Interpro)
Interpro ID Name
 IPR009360  Pre-mRNA-splicing factor Isy1
 IPR037200  Pre-mRNA-splicing factor Isy1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000350 generation of catalytic spliceosome for second transesterification step IEA
 biological_processGO:0000389 mRNA 3"-splice site recognition IBA
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0000974 Prp19 complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0071012 catalytic step 1 spliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IDA
 cellular_componentGO:0071014 post-mRNA release spliceosomal complex IBA
 cellular_componentGO:0071020 post-spliceosomal complex IBA
 molecular_functionGO:0000384 first spliceosomal transesterification activity IBA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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