ENSG00000241058


Homo sapiens

Features
Gene ID: ENSG00000241058
  
Biological name :NSUN6
  
Synonyms : NOP2/Sun RNA methyltransferase family member 6 / NSUN6 / Q8TEA1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: p12.31
Gene start: 18545561
Gene end: 18659285
  
Corresponding Affymetrix probe sets: 230200_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486203
Ensembl peptide - ENSP00000366519
Ensembl peptide - ENSP00000476221
NCBI entrez gene - 221078     See in Manteia.
OMIM - 617199
RefSeq - XM_017015914
RefSeq - NM_001351115
RefSeq - NM_182543
RefSeq - XM_017015909
RefSeq - XM_017015910
RefSeq - XM_017015911
RefSeq - XM_017015912
RefSeq - XM_017015913
RefSeq - XM_011519383
RefSeq - XM_011519384
RefSeq - XM_011519385
RefSeq - XM_011519386
RefSeq - XM_011519387
RefSeq - XM_011519389
RefSeq - XM_017015906
RefSeq - XM_017015907
RefSeq - XM_017015908
RefSeq Peptide - NP_001338044
RefSeq Peptide - NP_872349
swissprot - Q8TEA1
swissprot - U3KQU2
swissprot - A0A0D9SF14
Ensembl - ENSG00000241058
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nsun6ENSDARG00000103478Danio rerio
 NSUN6ENSGALG00000008564Gallus gallus
 Nsun6ENSMUSG00000026707Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NOP2 / P46087 / NOP2 nucleolar proteinENSG0000011164124
NSUN4 / Q96CB9 / NOP2/Sun RNA methyltransferase family member 4ENSG0000011748117
NSUN3 / Q9H649 / NOP2/Sun RNA methyltransferase family member 3ENSG0000017869416


Protein motifs (from Interpro)
Interpro ID Name
 IPR001678  SAM-dependent methyltransferase RsmB/NOP2-type
 IPR002478  PUA domain
 IPR015947  PUA-like superfamily
 IPR018314  Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site
 IPR023267  RNA (C5-cytosine) methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR036974  PUA domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006400 tRNA modification TAS
 biological_processGO:0030488 tRNA methylation IEA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000049 tRNA binding IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016428 tRNA (cytosine-5-)-methyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
tRNA modification in the nucleus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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