ENSG00000241484


Homo sapiens

Features
Gene ID: ENSG00000241484
  
Biological name :ARHGAP8
  
Synonyms : ARHGAP8 / P85298 / Rho GTPase activating protein 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.31
Gene start: 44752558
Gene end: 44862788
  
Corresponding Affymetrix probe sets: 1555162_at (Human Genome U133 Plus 2.0 Array)   205980_s_at (Human Genome U133 Plus 2.0 Array)   232567_at (Human Genome U133 Plus 2.0 Array)   37117_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000374424
Ensembl peptide - ENSP00000403618
Ensembl peptide - ENSP00000402775
Ensembl peptide - ENSP00000379425
Ensembl peptide - ENSP00000337287
Ensembl peptide - ENSP00000348407
Ensembl peptide - ENSP00000374422
NCBI entrez gene - 23779     See in Manteia.
OMIM - 609405
RefSeq - NM_001017526
RefSeq - NM_001198726
RefSeq - NM_181335
RefSeq Peptide - NP_851852
RefSeq Peptide - NP_001017526
RefSeq Peptide - NP_001185655
swissprot - P85298
swissprot - B1AHC2
swissprot - F8W6F4
swissprot - F8WCV8
swissprot - B1AHF8
Ensembl - ENSG00000241484
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGAP8ENSGALG00000019261Gallus gallus
 Q9CXP4ENSMUSG00000078954Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRR5-ARHGAP8 / PRR5-ARHGAP8 readthroughENSG0000024840593
Q07960 / ARHGAP1 / Rho GTPase activating protein 1ENSG0000017522047
PRUNE2 / Q8WUY3 / prune homolog 2ENSG0000010677214
ATCAY / Q86WG3 / ATCAY, caytaxinENSG0000016765414
BNIP2 / Q12982 / BCL2 interacting protein 2ENSG0000014029913
BNIPL / Q7Z465 / BCL2 interacting protein likeENSG0000016314112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR008936  Rho GTPase activation protein
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005096 GTPase activator activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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