ENSG00000248405


Homo sapiens

Features
Gene ID: ENSG00000248405
  
Biological name :PRR5-ARHGAP8
  
Synonyms : PRR5-ARHGAP8 / PRR5-ARHGAP8 readthrough
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.31
Gene start: 44702233
Gene end: 44862706
  
Corresponding Affymetrix probe sets: 1555162_at (Human Genome U133 Plus 2.0 Array)   205980_s_at (Human Genome U133 Plus 2.0 Array)   37117_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262731
Ensembl peptide - ENSP00000425026
Ensembl peptide - ENSP00000354732
NCBI entrez gene - 553158     See in Manteia.
RefSeq - NM_181334
RefSeq Peptide - NP_851851
swissprot - B1AHC4
swissprot - B1AHC3
swissprot - H0Y9T8
Ensembl - ENSG00000248405
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARHGAP8ENSGALG00000019261Gallus gallus
 Q9CXP4ENSMUSG00000078954Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P85298 / ARHGAP8 / Rho GTPase activating protein 8ENSG0000024148477
Q07960 / ARHGAP1 / Rho GTPase activating protein 1ENSG0000017522040
PRUNE2 / Q8WUY3 / prune homolog 2ENSG0000010677216
ATCAY / Q86WG3 / ATCAY, caytaxinENSG0000016765413
BNIP2 / Q12982 / BCL2 interacting protein 2ENSG0000014029912
BNIPL / Q7Z465 / BCL2 interacting protein likeENSG0000016314112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001251  CRAL-TRIO lipid binding domain
 IPR008936  Rho GTPase activation protein
 IPR013745  TORC2 component Bit61/PRR5
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IBA
 cellular_componentGO:0005737 cytoplasm IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr