ENSG00000242372


Homo sapiens

Features
Gene ID: ENSG00000242372
  
Biological name :EIF6
  
Synonyms : EIF6 / eukaryotic translation initiation factor 6 / P56537
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q11.22
Gene start: 35278911
Gene end: 35284985
  
Corresponding Affymetrix probe sets: 210213_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411450
Ensembl peptide - ENSP00000363559
Ensembl peptide - ENSP00000390897
Ensembl peptide - ENSP00000395907
Ensembl peptide - ENSP00000415044
Ensembl peptide - ENSP00000363566
Ensembl peptide - ENSP00000363574
NCBI entrez gene - 3692     See in Manteia.
OMIM - 602912
RefSeq - NM_181468
RefSeq - NM_001267810
RefSeq - NM_002212
RefSeq - NM_181466
RefSeq Peptide - NP_001254739
RefSeq Peptide - NP_852133
RefSeq Peptide - NP_852131
RefSeq Peptide - NP_002203
swissprot - P56537
swissprot - A0A0B4J1Y7
swissprot - B7ZBH1
swissprot - F8WD20
swissprot - F8WDS6
Ensembl - ENSG00000242372
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif6ENSDARG00000020232Danio rerio
 EIF6ENSGALG00000033993Gallus gallus
 Eif6ENSMUSG00000027613Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AL121753.1ENSG0000026158239


Protein motifs (from Interpro)
Interpro ID Name
 IPR002769  Translation initiation factor IF6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000054 ribosomal subunit export from nucleus IBA
 biological_processGO:0000460 maturation of 5.8S rRNA IBA
 biological_processGO:0000470 maturation of LSU-rRNA IBA
 biological_processGO:0006110 regulation of glycolytic process ISS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0032868 response to insulin ISS
 biological_processGO:0035195 gene silencing by miRNA IMP
 biological_processGO:0035278 miRNA mediated inhibition of translation IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0042256 mature ribosome assembly IEA
 biological_processGO:0042304 regulation of fatty acid biosynthetic process ISS
 biological_processGO:0045652 regulation of megakaryocyte differentiation ISS
 biological_processGO:0045727 positive regulation of translation ISS
 biological_processGO:1902626 assembly of large subunit precursor of preribosome IBA
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process ISS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0030687 preribosome, large subunit precursor IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043022 ribosome binding IEA
 molecular_functionGO:0043023 ribosomal large subunit binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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