ENSG00000250264


Homo sapiens

Features
Gene ID: ENSG00000250264
  
Biological name :AL669918.1
  
Synonyms : AL669918.1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.32
Gene start: 32813767
Gene end: 32838822
  
Corresponding Affymetrix probe sets: 205671_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391806
swissprot - E7ENX8
Ensembl - ENSG00000250264
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tap2aENSDARG00000036787Danio rerio
 tap2tENSDARG00000033446Danio rerio
 TAP2ENSGALG00000029381Gallus gallus
 Tap2ENSMUSG00000024339Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAP2 / Q03519 / transporter 2, ATP binding cassette subfamily B memberENSG0000020426779
ABCB9 / Q9NP78 / ATP binding cassette subfamily B member 9ENSG0000015096732
TAP1 / Q03518 / transporter 1, ATP binding cassette subfamily B memberENSG0000016839430
ABCB10 / Q9NRK6 / ATP binding cassette subfamily B member 10ENSG0000013577624
ABCB8 / Q9NUT2 / ATP binding cassette subfamily B member 8ENSG0000019715024


Protein motifs (from Interpro)
Interpro ID Name
 IPR000353  MHC class II, beta chain, N-terminal
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR003597  Immunoglobulin C1-set
 IPR005293  Antigen peptide transporter 2
 IPR007110  Immunoglobulin-like domain
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR013305  ABC transporter Tap-like
 IPR013783  Immunoglobulin-like fold
 IPR014745  MHC class II, alpha/beta chain, N-terminal
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036640  ABC transporter type 1, transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0015833 peptide transport IEA
 biological_processGO:0019882 antigen processing and presentation IEA
 biological_processGO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0042613 MHC class II protein complex IEA
 cellular_componentGO:0042825 TAP complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015440 peptide-transporting ATPase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042287 MHC protein binding IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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