ENSGALG00000029381


Gallus gallus

Features
Gene ID: ENSGALG00000029381
  
Biological name :TAP2
  
Synonyms : TAP2
  
Possible biological names infered from orthology : AL669918.1 / P36371 / Q03519 / transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) / transporter 2, ATP binding cassette subfamily B member
  
Species: Gallus gallus
  
Chr. number: 16
Strand: -1
Band:
Gene start: 78333
Gene end: 81467
  
Corresponding Affymetrix probe sets: Gga.2865.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044374
NCBI entrez gene - 427728     See in Manteia.
RefSeq - NM_001099357
RefSeq - XM_015294990
RefSeq - XM_015294991
RefSeq Peptide - NP_001092827
swissprot - A5HUM1
Ensembl - ENSGALG00000029381
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tap2aENSDARG00000036787Danio rerio
 tap2tENSDARG00000033446Danio rerio
 AL669918.1ENSG00000250264Homo sapiens
 TAP2ENSG00000204267Homo sapiens
 Tap2ENSMUSG00000024339Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCB9 / ATP binding cassette subfamily B member 9 / Q9JJ59* / Q9NP78* / ATP-binding cassette, sub-family B (MDR/TAP), member 9*ENSGALG0000000373636
TAP1 / antigen peptide transporter 1 / Q03518* / P21958* / transporter 1, ATP binding cassette subfamily B member* / transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)*ENSGALG0000003507530
ABCB10 / ATP binding cassette subfamily B member 10 / Q9JI39* / Q9NRK6* / ATP-binding cassette, sub-family B (MDR/TAP), member 10*ENSGALG0000001109626


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR005293  Antigen peptide transporter 2
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity IEA
 biological_processGO:0002237 response to molecule of bacterial origin IEA
 biological_processGO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent IEA
 biological_processGO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent IEA
 biological_processGO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent IEA
 biological_processGO:0015833 peptide transport IEA
 biological_processGO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IEA
 biological_processGO:0042886 amide transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0042825 TAP complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015440 peptide-transporting ATPase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042287 MHC protein binding IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA
 molecular_functionGO:0046978 TAP1 binding IEA


Pathways (from Reactome)
Pathway description
ER-Phagosome pathway
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008022 TAPBP / TAP binding protein / O15533*  / reaction
 ENSGALG00000039704 Q5ZJW4 / SEC22B / Vesicle-trafficking protein SEC22b / O08547* / O75396* / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr