ENSG00000274736


Homo sapiens

Features
Gene ID: ENSG00000274736
  
Biological name :CCL23
  
Synonyms : CCL23 / C-C motif chemokine ligand 23 / P55773
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 36013056
Gene end: 36017968
  
Corresponding Affymetrix probe sets: 210548_at (Human Genome U133 Plus 2.0 Array)   210549_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481357
Ensembl peptide - ENSP00000484748
Ensembl peptide - ENSP00000479076
NCBI entrez gene - 6368     See in Manteia.
OMIM - 602494
RefSeq - NM_005064
RefSeq - NM_145898
RefSeq Peptide - NP_005055
RefSeq Peptide - NP_665905
swissprot - A0A087WV09
swissprot - P55773
Ensembl - ENSG00000274736
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ccl6ENSMUSG00000018927Mus musculus
 Ccl9ENSMUSG00000019122Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCL15 / Q16663 / C-C motif chemokine ligand 15ENSG0000027571859
CCL15-CCL14 / CCL15-CCL14 readthrough (NMD candidate)ENSG0000027568859


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IC
 biological_processGO:0006874 cellular calcium ion homeostasis TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:2001264 negative regulation of C-C chemokine binding IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0031726 CCR1 chemokine receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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