ENSG00000275718


Homo sapiens

Features
Gene ID: ENSG00000275718
  
Biological name :CCL15
  
Synonyms : CCL15 / C-C motif chemokine ligand 15 / Q16663
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 35996440
Gene end: 36002038
  
Corresponding Affymetrix probe sets: 210390_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484078
Ensembl peptide - ENSP00000484262
NCBI entrez gene - 6359     See in Manteia.
OMIM - 601393
RefSeq - NM_032965
swissprot - A0A087X1J9
swissprot - Q16663
Ensembl - ENSG00000275718
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ccl6ENSMUSG00000018927Mus musculus
 Ccl9ENSMUSG00000019122Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCL15-CCL14 / CCL15-CCL14 readthrough (NMD candidate)ENSG00000275688100
CCL23 / P55773 / C-C motif chemokine ligand 23ENSG0000027473672


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR030592  C-C motif chemokine 15
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006874 cellular calcium ion homeostasis TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005102 signaling receptor binding TAS
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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