ENSMUSG00000018927


Mus musculus

Features
Gene ID: ENSMUSG00000018927
  
Biological name :Ccl6
  
Synonyms : Ccl6 / C-C motif chemokine 6 CCL6(22-95) CCL6(23-95) / P27784
  
Possible biological names infered from orthology : CCL15 / CCL15-CCL14 / CCL15-CCL14 readthrough (NMD candidate) / CCL23 / C-C motif chemokine ligand 15 / C-C motif chemokine ligand 23 / P55773 / Q16663
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: C
Gene start: 83587882
Gene end: 83593087
  
Corresponding Affymetrix probe sets: 10389222 (MoGene1.0st)   1417266_at (Mouse Genome 430 2.0 Array)   1420249_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019071
NCBI entrez gene - 20305     See in Manteia.
MGI - MGI:98263
RefSeq - NM_009139
RefSeq Peptide - NP_033165
swissprot - P27784
Ensembl - ENSMUSG00000018927
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCL15ENSG00000275718Homo sapiens
 CCL15-CCL14ENSG00000275688Homo sapiens
 CCL23ENSG00000274736Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccl9 / P51670 / C-C motif chemokine 9 CCL9(29-101) CCL9(30-101) CCL9(31-101) / CCL15* / CCL23* / Q16663* / P55773* / CCL15-CCL14* / C-C motif chemokine ligand 15* / C-C motif chemokine liga...ENSMUSG0000001912248


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000079700 Fpr3 / O08790 / Formyl peptide receptor-related sequence 1 / FPR2* / P25090* / formyl peptide receptor 2*  / complex / reaction
 ENSMUSG00000052270 Fpr2 / O88536 / Formyl peptide receptor 2 / P25090*  / complex / reaction






 

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