ENSMUSG00000019122


Mus musculus

Features
Gene ID: ENSMUSG00000019122
  
Biological name :Ccl9
  
Synonyms : Ccl9 / C-C motif chemokine 9 CCL9(29-101) CCL9(30-101) CCL9(31-101) / P51670
  
Possible biological names infered from orthology : CCL15 / CCL15-CCL14 / CCL15-CCL14 readthrough (NMD candidate) / CCL23 / C-C motif chemokine ligand 15 / C-C motif chemokine ligand 23 / P55773 / Q16663
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: C
Gene start: 83572919
Gene end: 83578636
  
Corresponding Affymetrix probe sets: 10389214 (MoGene1.0st)   1417936_at (Mouse Genome 430 2.0 Array)   1448898_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019266
NCBI entrez gene - 20308     See in Manteia.
MGI - MGI:104533
RefSeq - NM_011338
RefSeq Peptide - NP_035468
swissprot - P51670
swissprot - Q3U9T8
Ensembl - ENSMUSG00000019122
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCL15ENSG00000275718Homo sapiens
 CCL15-CCL14ENSG00000275688Homo sapiens
 CCL23ENSG00000274736Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccl6 / P27784 / C-C motif chemokine 6 CCL6(22-95) CCL6(23-95) / CCL15* / CCL23* / Q16663* / P55773* / CCL15-CCL14* / C-C motif chemokine ligand 15* / C-C motif chemokine ligand 23* / CCL15-...ENSMUSG0000001892746


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0045662 negative regulation of myoblast differentiation IMP
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
G alpha (i) signalling events
Formyl peptide receptors bind formyl peptides and many other ligands


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Catsper3tm1.1(KOMP)Vlcg/Catsper3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Catsper3tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000052270 Fpr2 / O88536 / Formyl peptide receptor 2 / P25090*  / complex / reaction
 ENSMUSG00000079700 Fpr3 / O08790 / Formyl peptide receptor-related sequence 1 / FPR2* / P25090* / formyl peptide receptor 2*  / complex / reaction






 

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