ENSG00000275700


Homo sapiens

Features
Gene ID: ENSG00000275700
  
Biological name :AATF
  
Synonyms : AATF / apoptosis antagonizing transcription factor / Q9NY61
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 36948875
Gene end: 37056871
  
Corresponding Affymetrix probe sets: 209165_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477848
Ensembl peptide - ENSP00000480472
Ensembl peptide - ENSP00000479926
Ensembl peptide - ENSP00000477881
NCBI entrez gene - 26574     See in Manteia.
OMIM - 608463
RefSeq - XM_011524611
RefSeq - NM_012138
RefSeq Peptide - NP_036270
swissprot - A0A087WW41
swissprot - A0A087WWS8
swissprot - Q9NY61
swissprot - A0A087WTH8
Ensembl - ENSG00000275700
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aatfENSDARG00000025467Danio rerio
 AATFENSGALG00000005420Gallus gallus
 AatfENSMUSG00000018697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012617  Apoptosis-antagonizing transcription factor, C-terminal
 IPR025160  AATF leucine zipper-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006974 cellular response to DNA damage stimulus IEP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IEA
 biological_processGO:0032929 negative regulation of superoxide anion generation IDA
 biological_processGO:0040016 embryonic cleavage IEA
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0042985 negative regulation of amyloid precursor protein biosynthetic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0043522 leucine zipper domain binding IEA
 molecular_functionGO:0048156 tau protein binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000064300 NGFR / P08138 / nerve growth factor receptor  / reaction / complex
 ENSG00000179222 MAGED1 / Q9Y5V3 / MAGE family member D1  / complex / reaction
 ENSG00000134259 NGF / P01138 / nerve growth factor  / reaction / complex






 

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