ENSG00000278139


Homo sapiens

Features
Gene ID: ENSG00000278139
  
Biological name :AL358075.4
  
Synonyms : AL358075.4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.1
Gene start: 46043661
Gene end: 46176488
  
Corresponding Affymetrix probe sets: 211580_s_at (Human Genome U133 Plus 2.0 Array)   241325_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000439913
NCBI entrez gene - 110117499     See in Manteia.
RefSeq - NM_001303427
RefSeq Peptide - NP_001290356
swissprot - F6TDL0
Ensembl - ENSG00000278139
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pik3r3bENSDARG00000034409Danio rerio
 ENSGALG00000010335Gallus gallus
 AL670603.1ENSMUSG00000111410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PIK3R3 / Q92569 / phosphoinositide-3-kinase regulatory subunit 3ENSG0000011746185
P27986 / PIK3R1 / phosphoinositide-3-kinase regulatory subunit 1ENSG0000014567569
AC007192.1ENSG0000026817364
O00459 / PIK3R2 / phosphoinositide-3-kinase regulatory subunit 2ENSG0000010564764


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001720  PI3K p85/p55 subunit
 IPR032498  PI3K p85 subunit, inter-SH2 domain
 IPR035020  PI3K p85 subunit, C-terminal SH2 domain
 IPR035022  PI3K p85 subunit, N-terminal SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008286 insulin receptor signaling pathway IBA
 biological_processGO:0043551 regulation of phosphatidylinositol 3-kinase activity IBA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IBA
 biological_processGO:2001275 positive regulation of glucose import in response to insulin stimulus ISS
 cellular_componentGO:0005942 phosphatidylinositol 3-kinase complex IBA
 molecular_functionGO:0035014 phosphatidylinositol 3-kinase regulator activity IEA
 molecular_functionGO:0046935 1-phosphatidylinositol-3-kinase regulator activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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